| Protein: | GRB2_RAT |
| Organism: | Rattus norvegicus |
| Length: | 217 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GRB2_RAT.
| Description | E-value | Query Range |
Subject Range |
|
|
4.0E-41 | [1..217] | [1..217] |
|
|
7.0E-41 | [1..217] | [1..217] |
|
|
8.0E-41 | [1..217] | [1..217] |
|
|
4.0E-40 | [1..217] | [1..217] |
|
|
5.0E-40 | [1..216] | [1..216] |
|
|
3.0E-39 | [1..216] | [1..216] |
|
|
3.0E-38 | [1..216] | [1..228] |
|
Region A: Residues: [1-217] |
1 11 21 31 41 51
| | | | | |
1 MEAIAKYDFK ATADDELSFK RGDILKVLNE ECDQNWYKAE LNGKDGFIPK NYIEMKPHPW 60
61 FFGKIPRAKA EEMLSKQRHD GAFLIRESES APGDFSLSVK FGNDVQHFKV LRDGAGKYFL 120
121 WVVKFNSLNE LVDYHRSTSV SRNQQIFLRD IEQVPQQPTY VQALFDFDPQ EDGELGFRRG 180
181 DFIHVMDNSD PNWWKGACHG QTGMFPRNYV TPVNRNV
|
| Detection Method: |  |
| Confidence: | 42.09691 |
| Match: | 1griA |
| Description: | Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| molecular transducer activity | 3.13508395312263 | bayes_pls_golite062009 |
| signal transducer activity | 3.13508395312263 | bayes_pls_golite062009 |
| epidermal growth factor receptor binding | 2.9751846707539 | bayes_pls_golite062009 |
| binding | 2.69791297400248 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.57554390739461 | bayes_pls_golite062009 |
| actin binding | 2.17709619225063 | bayes_pls_golite062009 |
| protein binding | 2.14586566310919 | bayes_pls_golite062009 |
| insulin receptor binding | 2.1238568876176 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.85015570449703 | bayes_pls_golite062009 |
| molecular adaptor activity | 1.81145713371725 | bayes_pls_golite062009 |
| receptor binding | 1.80554013976158 | bayes_pls_golite062009 |
| kinase activity | 1.78069536883109 | bayes_pls_golite062009 |
| protein kinase activity | 1.64363774024605 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.59739467025045 | bayes_pls_golite062009 |
| SH3/SH2 adaptor activity | 1.59474164216385 | bayes_pls_golite062009 |
| transferase activity | 1.19152443245584 | bayes_pls_golite062009 |
| actin filament binding | 1.03574214978228 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase regulator activity | 1.03150090191995 | bayes_pls_golite062009 |
| insulin-like growth factor receptor binding | 0.950445630788802 | bayes_pls_golite062009 |
| transporter activity | 0.896907103596953 | bayes_pls_golite062009 |
| protein binding, bridging | 0.83823250804321 | bayes_pls_golite062009 |
| transcription regulator activity | 0.786324379459923 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.713068405985864 | bayes_pls_golite062009 |
| nucleic acid binding | 0.696368655705791 | bayes_pls_golite062009 |
| protein complex binding | 0.65988681496356 | bayes_pls_golite062009 |
| protein phosphorylated amino acid binding | 0.649814096718101 | bayes_pls_golite062009 |
| DNA binding | 0.578730664467311 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.456661966897198 | bayes_pls_golite062009 |
| sevenless binding | 0.418968910155118 | bayes_pls_golite062009 |
| phosphotyrosine binding | 0.311079584914389 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 0.29798436765753 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.245869952317152 | bayes_pls_golite062009 |
| structural molecule activity | 0.236653863910566 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 0.206747304356052 | bayes_pls_golite062009 |
| phosphoprotein binding | 0.16798254471727 | bayes_pls_golite062009 |
| kinase binding | 0.131981353175621 | bayes_pls_golite062009 |
| receptor signaling protein activity | 0.0443241110585009 | bayes_pls_golite062009 |
| transcription factor activity | 0.0291114923524518 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.0273219613963591 | bayes_pls_golite062009 |
