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View Structure Prediction Details

Protein: gi|124000565, gi...
Organism: synthetic construct
Length: 827 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|124000565, gi....

Description E-value Query
Range		 Subject
Range
gi|33303747 - gi|33303747|gb|AAQ02387.1| phosphofructokinase, liver [synthetic construct]
 0.0 [47..827] [5..780]
PFKL - phosphofructokinase, liver
gi|114684644, gi... - gi|114684644|ref|XP_001150758.1| PREDICTED: liver phosphofructokinase isoform 12 [Pan troglodytes], ...
 0.0 [47..827] [5..780]
PFKAL_PONAB - ATP-dependent 6-phosphofructokinase, liver type OS=Pongo abelii GN=PFKL PE=2 SV=1
K6PL_PONPY - 6-phosphofructokinase, liver type - Pongo pygmaeus (Orangutan)
 0.0 [47..827] [5..780]
gi|114684652 - gi|114684652|ref|XP_001150233.1| PREDICTED: liver phosphofructokinase isoform 5 [Pan troglodytes]
 0.0 [47..827] [5..780]
PFKAL_RAT - ATP-dependent 6-phosphofructokinase, liver type OS=Rattus norvegicus GN=Pfkl PE=1 SV=3
 0.0 [61..827] [14..780]
PFKAL_MOUSE - ATP-dependent 6-phosphofructokinase, liver type OS=Mus musculus GN=Pfkl PE=1 SV=4
 0.0 [61..827] [14..780]

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Predicted Domain #1
Region A:
Residues: [1-408] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCNQGRGRES SRGGLHVQGS CRGLSRSPQQ ETGFAKAPAG TDCFFHCSPG SRGQGDRKEE  60
   61 VTSEPGGTSI MSRLGGMNAA VRAVTRMGIY VGAKVFLIYE GYEGLVEGGE NIKQANWLSV 120
  121 SNIIQLGGTI IGSARCKAFT TREGRRAAAY NLVQHGITNL CVIGGDGSLT GANIFRSEWG 180
  181 SLLEELVAEG KISETTARTY SHLNIAGLVG SIDNDFCGTD MTIGTDSALH RIMEVIDAIT 240
  241 TTAQSHQRTF VLEVMGRHCG YLALVSALAS GADWLFIPEA PPEDGWENFM CERLGETRSR 300
  301 GSRLNIIIIA EGAIDRNGKP ISSSYVKDLV VQRLGFDTRV TVLGHVQRGG TPSAFDRILS 360
  361 SKMGMEAVMA LLEATPDTPA CVVTLSGNQS VRLPLMECVQ MTKEVQKA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 107.0
Match: 6pfkA
Description: ATP-dependent phosphofructokinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
6-phosphofructokinase activity 12.7403693686468 bayes_pls_golite062009
phosphofructokinase activity 11.7059647240147 bayes_pls_golite062009
fructose-6-phosphate binding 9.55959144901554 bayes_pls_golite062009
fructose binding 9.55841643584799 bayes_pls_golite062009
carbohydrate kinase activity 9.54757838113048 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 3.19280659830412 bayes_pls_golite062009
kinase activity 2.85624705588769 bayes_pls_golite062009
fructose-2,6-bisphosphate 2-phosphatase activity 2.7198911999025 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 2.67472251964197 bayes_pls_golite062009
sugar binding 2.21212411210899 bayes_pls_golite062009
monosaccharide binding 2.05358532613083 bayes_pls_golite062009
transferase activity 1.97789134877808 bayes_pls_golite062009
catalytic activity 1.89212073381079 bayes_pls_golite062009
protein binding 1.76136621968843 bayes_pls_golite062009
binding 1.57437723650762 bayes_pls_golite062009
carbohydrate binding 0.97067862054315 bayes_pls_golite062009
hydrolase activity 0.276140444059183 bayes_pls_golite062009
cytoskeletal protein binding 0.184982121995695 bayes_pls_golite062009
tubulin binding 0.0889554716245424 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [409-827] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDKRFDEAT QLRGGSFENN WNIYKLLAHQ KPPKEKSNFS LAILNVGAPA AGMNAAVRSA  60
   61 VRTGISHGHT VYVVHDGFEG LAKGQVQEVG WHDVAGWLGR GGSMLGTKRT LPKGQLESIV 120
  121 ENIRIYGIHA LLVVGGFEAY EGVLQLVEAR GRYEELCIVM CVIPATISNN VPGTDFSLGS 180
  181 DTAVNAAMES CDRIKQSASG TKRRVFIVET MGGYCGYLAT VTGIAVGADA AYVFEDPFNI 240
  241 HDLKVNVEHM TEKMKTDIQR GLVLRNEKCH DYYTTEFLYN LYSSEGKGVF DCRTNVLGHL 300
  301 QQGGAPTPFD RNYGTKLGVK AMLWLSEKLR EVYRKGRVFA NAPDSACVIG LKKKAVAFSP 360
  361 VTELKKDTDF EHRMPREQWW LSLRLMLKML AQYRISMAAY VSGELEHVTR RTLSMDKGF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 74.154902
Match: 2higA
Description: No description for 2higA was found.
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle