YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|123995269, gi...
Organism:	synthetic construct
Length:	220 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|123995269, gi....

Description	E-value	Query Range	Subject Range
CREG1_MOUSE - Protein CREG1 OS=Mus musculus GN=Creg1 PE=1 SV=1	4.0E-65	[1..220]	[1..220]
gi\|183986027, gi... - gi\|183986027\|gb\|AAI66446.1\| Cellular repressor of E1A-stimulated genes 1 [Rattus norvegicus], gi\|157...	6.0E-63	[1..220]	[1..220]
gi\|114560951 - gi\|114560951\|ref\|XP_001157266.1\| PREDICTED: similar to cellular repressor of E1A-stimulated genes CR...	1.0E-61	[3..220]	[118..335]
gi\|109019411 - gi\|109019411\|ref\|XP_001089325.1\| PREDICTED: similar to cellular repressor of E1A-stimulated genes [M...	8.0E-61	[1..220]	[1..220]
gi\|21754713 - gi\|21754713\|dbj\|BAC04550.1\| unnamed protein product [Homo sapiens]	1.0E-59	[1..220]	[1..212]
gi\|115495283, gi... - gi\|115495283\|ref\|NP_001069410.1\| cellular repressor of E1A-stimulated genes [Bos taurus], gi\|1099400...	2.0E-55	[1..220]	[1..221]
CREG-PB, CREG-PA... - The gene Cellular Repressor of E1A-stimulated Genes is referred to in FlyBase by the symbol Dmel\CRE... gi\|220959066, gi... - gi\|220959066\|gb\|ACL92076.1\| CREG-PA [synthetic construct], gi\|220950050\|gb\|ACL87568.1\| CREG-PA [synt...	1.0E-51	[10..218]	[1..210]

Back

Predicted Domain #1

Region A:
Residues: [1-220]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGLSRGSAR ALLAALLAST LLALLVSPAR GRGGRDHGDW DEASRLPPLP PREDAARVAR  60
   61 FVTHVSDWGA LATISTLEAV RGRPFADVLS LSDGPPGAGS GVPYFYLSPL QLSVSNLQEN 120
  121 PYATLTMTLA QTNFCKKHGF DPQSPLCVHI MLSGTVTKVN ETEMDIAKHS LFIRHPEMKT 180
  181 WPSSHNWFFA KLNITNIWVL DYFGGPKIVT PEEYYNVTVQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	55.522879
Match:	1xhnA
Description:	The crystal structure of Cellular Repressor of E1A-stimulated Genes (CREG)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	2.31887334511829	bayes_pls_golite062009
binding	1.60534132207804	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.742363624852308	bayes_pls_golite062009
catalytic activity	0.660906721832294	bayes_pls_golite062009
transcription factor binding	0.463016643940605	bayes_pls_golite062009
protein binding	0.222179736788716	bayes_pls_golite062009
transcription repressor activity	0.0167144924052265	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: