YRC Public Data Repository - Protein Structure Prediction

Protein:	MTPN_RAT
Organism:	Rattus norvegicus
Length:	118 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MTPN_RAT.

Description	E-value	Query Range	Subject Range
gi\|28373837 - gi\|28373837\|pdb\|1N0R\|A Chain A, 4ank: A Designed Ankyrin Repeat Protein With Four Identical Consensu...	166.0	[0..2]	[118..2]
gi\|115621182, gi... - gi\|115951148\|ref\|XP_001197526.1\| PREDICTED: similar to ankyrin 2,3/unc44 [Strongylocentrotus purpura...	164.0	[0..2]	[118..210]
gi\|115433911, gi... - gi\|115433911\|ref\|XP_001217610.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	156.0	[0..2]	[118..1035]
gi\|108868779, gi... - gi\|157106769\|ref\|XP_001649474.1\| ankyrin 2,3/unc44 [Aedes aegypti], gi\|108868779\|gb\|EAT33004.1\| anky...	156.0	[0..2]	[118..52]
gi\|85701704, gi\|... - gi\|85701704\|ref\|NP_001028370.1\| ankyrin repeat domain 50 [Mus musculus], gi\|74194058\|dbj\|BAE36940.1\|...	154.0	[0..2]	[118..19]
gi\|109075425 - gi\|109075425\|ref\|XP_001095471.1\| PREDICTED: ankyrin 2, neuronal isoform 12 [Macaca mulatta]	153.0	[0..2]	[118..233]
gi\|4803663 - gi\|4803663\|emb\|CAB42644.1\| ankyrin B (440 kDa) [Homo sapiens]	153.0	[0..2]	[118..233]
gi\|109467596 - gi\|109467596\|ref\|XP_001076082.1\| PREDICTED: similar to ankyrin 2 isoform 1 [Rattus norvegicus]	153.0	[0..2]	[118..233]

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Predicted Domain #1

Region A:
Residues: [1-118]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCDKEFMWAL KNGDLDEVKD YVAKGEDVNR TLEGGRKPLH YAADCGQLEI LEFLLLKGAD  60
   61 INAPDKHHIT PLLSAVYEGH VSCVKLLLSK GADKTVKGPD GLTALEATDN QAIKALLQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	24.154902
Match:	1myoA
Description:	SOLUTION STRUCTURE OF MYOTROPHIN, NMR, 44 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.96927469603571	bayes_pls_golite062009
protein binding	1.64872738860757	bayes_pls_golite062009
cytoskeletal protein binding	1.21219115228238	bayes_pls_golite062009
transcription regulator activity	0.926380650892541	bayes_pls_golite062009
nucleic acid binding	0.620392456397365	bayes_pls_golite062009
structural molecule activity	0.54429752415035	bayes_pls_golite062009
DNA binding	0.490127111900304	bayes_pls_golite062009
transcription factor binding	0.12341410494194	bayes_pls_golite062009
transcription factor activity	0.0143665682178068	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: