YRC Public Data Repository - Protein Structure Prediction

Protein:	SIA1A_MOUSE
Organism:	Mus musculus
Length:	282 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SIA1A_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|76640366 - gi\|76640366\|ref\|XP_875974.1\| PREDICTED: similar to seven in absentia homolog 1 isoform b [Bos taurus...	303.0	[0..1]	[282..254]
gi\|50753723 - gi\|50753723\|ref\|XP_414105.1\| PREDICTED: similar to SIAH1 protein [Gallus gallus]	301.0	[0..1]	[282..370]
gi\|55749557, gi\|... - gi\|55749557\|ref\|NP_001006611.1\| seven in absentia homolog 1 isoform b [Homo sapiens], gi\|27503514\|gb... CCDS32444.1_1 - null gi\|109128439 - gi\|109128439\|ref\|XP_001114300.1\| PREDICTED: seven in absentia homolog 1 (Drosophila) isoform 1 [Maca... gi\|55749557 - ref\|NP_001006611.1\| seven in absentia homolog 1 isoform b [Homo sapiens] ENSPTRT00000014925 - null	296.0	[0..1]	[282..32]
gi\|68389919 - gi\|68389919\|ref\|XP_707669.1\| PREDICTED: similar to Seven in absentia 1A isoform 2 [Danio rerio]	296.0	[0..1]	[282..53]
gi\|57043872 - gi\|57043872\|ref\|XP_544419.1\| PREDICTED: similar to seven in absentia homolog 1 isoform b isoform 1 [...	295.0	[0..1]	[282..32]
gi\|62751353, gi\|... - gi\|62751353\|ref\|NP_001015836.1\| seven in absentia homolog 1 [Xenopus (Silurana) tropicalis], gi\|5847... gi\|49117837, gi\|... - gi\|49117837\|gb\|AAH72747.1\| MGC79105 protein [Xenopus laevis], gi\|148231169\|ref\|NP_001085438.1\| MGC79...	293.0	[0..1]	[282..1]
gi\|60654479 - gi\|60654479\|gb\|AAX29930.1\| seven in absentia-like 1 [synthetic construct]	292.0	[0..1]	[282..1]
gi\|123994983, gi... - gi\|61364081\|gb\|AAX42488.1\| seven in absentia-like 1 [synthetic construct], gi\|123994983\|gb\|ABM85093.... gi\|109128441 - gi\|109128441\|ref\|XP_001114318.1\| PREDICTED: seven in absentia homolog 1 isoform 2 [Macaca mulatta] gi\|55666665 - gi\|55666665\|ref\|XP_520625.1\| PREDICTED: seven in absentia homolog 1 [Pan troglodytes] gi\|55749567 - ref\|NP_001006612.1\| seven in absentia homolog 1 isoform c [Homo sapiens] SIAH1 - seven in absentia homolog 1 (Drosophila)	292.0	[0..1]	[282..1]

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Predicted Domain #1

Region A:
Residues: [1-96]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRQTATALP TGTSKCPPSQ RVPALTGTTA SNNDLASLFE CPVCFDYVLP PILQCQSGHL  60
   61 VCSNCRPKLT CCPTCRGPLG SIRNLAMEKV ANSVLF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10.0
Match:	2cklB
Description:	No description for 2cklB was found.

Predicted Domain #2

Region A:
Residues: [97-282]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PCKYASSGCE ITLPHTEKAE HEELCEFRPY SCPCPGASCK WQGSLDAVMP HLMHQHKSIT  60
   61 TLQGEDIVFL ATDINLPGAV DWVMMQSCFG FHFMLVLEKQ EKYDGHQQFF AIVQLIGTRK 120
  121 QAENFAYRLE LNGHRRRLTW EATPRSIHEG IATAIMNSDC LVFDTSIAQL FAENGNLGIN 180
  181 VTISMC

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	57.0
Match:	2a25A
Description:	Crystal structure of Siah1 SBD bound to the peptide EKPAAVVAPITTG from SIP
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits