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View Structure Prediction Details

Protein: RAE1E_MOUSE
Organism: Mus musculus
Length: 251 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RAE1E_MOUSE.

Description E-value Query
Range
Subject
Range
gi|108743887 - gi|108743887|gb|ABG02212.1| MHC class I antigen [Pan troglodytes]
441.0 [0..3] [246..1]
gi|2118771, gi|1... - gi|238799604|gb|ACR55722.1| MHC class I antigen [Homo sapiens], pir||I54493 MHC class I histocompati...
437.0 [0..3] [246..1]
gi|15808079 - gi|15808079|gb|AAK67482.1| MHC class I antigen [Pongo pygmaeus]
434.0 [0..3] [246..1]

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Predicted Domain #1
Region A:
Residues: [1-251]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKAAVTKRH HFMIQKLLIL LSYGYTNGLD DAHSLRCNLT IKDPTSADLP WCDVKCSVDE  60
   61 ITILHLNNIN KTMTSGDPGK MANATGKCLT QPLNDLCQEL RDKVSNTKVD THKTNGYPHL 120
  121 QVTMIYPQSQ GQTPSATWEF NISDSYFFTF YTENMSWRSA NDESGVIMNK WKDDGDLVQQ 180
  181 LKYFIPQCRQ KIDEFLKQSK EKPRSTSRSP SITQLTSTSP LPPPSHSTSK KGFISVGLIF 240
  241 ISLLFAFAFA M

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.09691
Match: 1jfmA
Description: NK cell ligand RAE-1 beta
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
olfactory receptor activity 5.33587116950969 bayes_pls_golite062009
antigen binding 4.46241992460507 bayes_pls_golite062009
peptide antigen binding 4.35858424470161 bayes_pls_golite062009
MHC class I receptor activity 3.41449694100623 bayes_pls_golite062009
endogenous lipid antigen binding 3.2718839441674 bayes_pls_golite062009
receptor activity 3.00266491683196 bayes_pls_golite062009
natural killer cell lectin-like receptor binding 2.87337850935774 bayes_pls_golite062009
transmembrane receptor activity 2.86520164199147 bayes_pls_golite062009
molecular transducer activity 2.56374296515227 bayes_pls_golite062009
signal transducer activity 2.56374296515227 bayes_pls_golite062009
protein binding 2.20481087437436 bayes_pls_golite062009
binding 1.90626658068048 bayes_pls_golite062009
IgG binding 1.85116965480634 bayes_pls_golite062009
lipid antigen binding 1.19229113780113 bayes_pls_golite062009
receptor binding 0.96769592478452 bayes_pls_golite062009
IgG receptor activity 0.93675845777404 bayes_pls_golite062009
G-protein coupled receptor activity 0.44365180492849 bayes_pls_golite062009
peptide binding 0.20607041314192 bayes_pls_golite062009
catalytic activity 0.115804452291889 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle