YRC Public Data Repository - Protein Structure Prediction

Protein:	CREG1_MOUSE
Organism:	Mus musculus
Length:	220 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CREG1_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|183986027, gi... - gi\|183986027\|gb\|AAI66446.1\| Cellular repressor of E1A-stimulated genes 1 [Rattus norvegicus], gi\|157...	239.0	[0..1]	[220..1]
CREG1 - cellular repressor of E1A-stimulated genes 1 gi\|123995269, gi... - gi\|208965960\|dbj\|BAG72994.1\| cellular repressor of E1A-stimulated genes 1 [synthetic construct], gi\|...	232.0	[0..1]	[220..1]
gi\|114560951 - gi\|114560951\|ref\|XP_001157266.1\| PREDICTED: similar to cellular repressor of E1A-stimulated genes CR...	228.0	[0..26]	[220..141]
gi\|109019411 - gi\|109019411\|ref\|XP_001089325.1\| PREDICTED: similar to cellular repressor of E1A-stimulated genes [M...	223.0	[0..1]	[220..1]
gi\|115495283, gi... - gi\|115495283\|ref\|NP_001069410.1\| cellular repressor of E1A-stimulated genes [Bos taurus], gi\|1099400...	206.0	[0..1]	[220..1]
gi\|26351825 - gi\|26351825\|dbj\|BAC39549.1\| unnamed protein product [Mus musculus]	201.0	[0..62]	[220..1]
CREG-PB, CREG-PA... - The gene Cellular Repressor of E1A-stimulated Genes is referred to in FlyBase by the symbol Dmel\CRE... gi\|220959066, gi... - gi\|220959066\|gb\|ACL92076.1\| CREG-PA [synthetic construct], gi\|220950050\|gb\|ACL87568.1\| CREG-PA [synt...	201.0	[0..6]	[218..1]

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Predicted Domain #1

Region A:
Residues: [1-220]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAARAPELAR SLLAALLAPA LVALLVSPAS GRGGRDHGDW DVDRRLPPLP PREDGPRVAR  60
   61 FVTHVSDWGS LATISTIKEV RGWPFADIIS ISDGPPGEGT GEPYMYLSPL QQAVSDLQEN 120
  121 PEATLTMSLA QTVYCRNHGF DPQSPLCVHI MMSGTVTKVN KTEEDYARDS LFVRHPEMKH 180
  181 WPSSHNWFFA KLKISRIWVL DYFGGPKVVT PEEYFNVTLQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	52.69897
Match:	1xhnA
Description:	The crystal structure of Cellular Repressor of E1A-stimulated Genes (CREG)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	2.31887334511829	bayes_pls_golite062009
binding	1.60534132207804	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.742363624852308	bayes_pls_golite062009
catalytic activity	0.660906721832294	bayes_pls_golite062009
transcription factor binding	0.463016643940605	bayes_pls_golite062009
protein binding	0.222179736788716	bayes_pls_golite062009
transcription repressor activity	0.0167144924052265	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: