YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|46560587, gi\|...
Organism:	Mus musculus
Length:	243 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|46560587, gi|....

Description	E-value	Query Range	Subject Range
gi\|114607646, gi... - gi\|114607648\|ref\|XP_518517.2\| PREDICTED: Down syndrome critical region gene 1-like 1 protein isoform...	430.0	[0..1]	[243..1]
gi\|55664041, gi\|... - gi\|55958966\|emb\|CAI16754.1\| Down syndrome critical region gene 1-like 1 [Homo sapiens], gi\|55664041\|...	430.0	[0..1]	[243..1]
gi\|109071383, gi... - gi\|109071389\|ref\|XP_001102066.1\| PREDICTED: Down syndrome critical region gene 1-like 1 isoform 3 [M...	428.0	[0..1]	[243..1]
gi\|113911991 - gi\|113911991\|gb\|AAI22720.1\| RCAN2 protein [Bos taurus]	427.0	[0..1]	[243..1]
gi\|149069266, gi... - gi\|56270299\|gb\|AAH86974.1\| Regulator of calcineurin 2 [Rattus norvegicus], gi\|28212228\|ref\|NP_783168...	414.0	[0..1]	[243..1]
gi\|56611177, gi\|... - gi\|89270941\|emb\|CAJ81764.1\| Down syndrome critical region gene 1-like 1 [Xenopus tropicalis], gi\|583...	358.0	[0..1]	[243..1]
gi\|74001209 - gi\|74001209\|ref\|XP_849295.1\| PREDICTED: similar to calcipressin 1 isoform a isoform 1 [Canis familia...	336.0	[0..34]	[243..45]
gi\|54697016, gi\|... - gi\|61367407\|gb\|AAX42993.1\| Down syndrome critical region gene 1-like 2 [synthetic construct], gi\|613...	331.0	[0..28]	[243..16]

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Predicted Domain #1

Region A:
Residues: [1-162]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRGDAYFIGM RSLGQQASIP EDGGLFFLCC IDRDWAVTQC FAEEAFQALT DFSDLPNSLF  60
   61 ACNVHQSVFE EEESKEKFEG LFRTYDECVT FQLFKSFRRV RINFSHPKSA ARARIELHET 120
  121 QFRGKKLKLY FAQVQTPETD GDKLHLAPPQ PAKQFLISPP SS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	36.69897
Match:	1weyA
Description:	Solution structure of RRM domain in calcipressin 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleic acid binding	4.11118333721636	bayes_pls_golite062009
binding	3.64400841800969	bayes_pls_golite062009
RNA binding	2.45916448091535	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.9432590957792	bayes_pls_golite062009
hydrolase activity	1.69824301409862	bayes_pls_golite062009
mRNA binding	1.62410365165765	bayes_pls_golite062009
transcription regulator activity	1.24650529385826	bayes_pls_golite062009
DNA binding	1.23082363146877	bayes_pls_golite062009
protein binding	1.12215421354121	bayes_pls_golite062009
transcription factor activity	0.426324573266235	bayes_pls_golite062009
sequence-specific DNA binding	0.0605038543305221	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [163-243]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPVGWKPISD ATPVLNYDLL YAVAKLGPGE KYELHAGTES TPSVVVHVCD SDMEEEEDPK  60
   61 TSPKPKIIQT RRPGLPPSVS N

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: