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View Structure Prediction Details

Protein: ubc-6
Organism: Caenorhabditis elegans
Length: 299 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ubc-6.

Description E-value Query
Range
Subject
Range
ubc-6 - Ubiquitin-conjugating enzyme status:Confirmed UniProt:Q18931 protein_id:AAB93334.2
269.0 [0..1] [299..16]

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Predicted Domain #1
Region A:
Residues: [1-184]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKEAMELRQP TEMYHAQPME DNLFEWHFTI RGTLGTDFEG GIYHGRIIFP ADYPMKPPNL  60
   61 ILLTPNGRFE LNKKVCLSIS GYHPETWLPS WSIRTALLAL IGFLPSTPGG ALGSLDYPPK 120
  121 ERQRLAKLSC EWKCKECGCV MKTALLPITE DGQLKQTEEA KTLAAQLKFQ DESVVKKEVE 180
  181 AANN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.522879
Match: 2f4wA
Description: Human ubiquitin-conjugating enzyme E2 J2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
small conjugating protein ligase activity 6.13787067729569 bayes_pls_golite062009
ubiquitin-protein ligase activity 6.13342835108038 bayes_pls_golite062009
acid-amino acid ligase activity 5.20679401190557 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 4.30935997378918 bayes_pls_golite062009
ligase activity 1.28816297541508 bayes_pls_golite062009
catalytic activity 0.891402822028799 bayes_pls_golite062009
binding 0.852142254811421 bayes_pls_golite062009
NEDD8 ligase activity 0.715654744941217 bayes_pls_golite062009
protein binding 0.470754319870613 bayes_pls_golite062009
protein kinase activity 0.0722326952092479 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [185-299]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QKNPTETEPS EETSSVPTEN VEESEEDADE REEGTTVNVN SSEVPDVAQP AVQPIRDPQP  60
   61 LVFQHHAPRL ASTNFDYTLL YKIPVIALCF AIFFTLLARR FLVDNLTSPK DGSEL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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