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View Structure Prediction Details

Protein: TDGF1_MOUSE
Organism: Mus musculus
Length: 171 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TDGF1_MOUSE.

Description E-value Query
Range
Subject
Range
gi|115893463, gi... - gi|115930648|ref|XP_001178590.1| PREDICTED: similar to fibropellin Ib [Strongylocentrotus purpuratus...
162.0 [0..12] [170..1576]
gi|27463074, gi|... - gi|47085727|ref|NP_998132.1| FAT tumor suppressor homolog 1 [Danio rerio], gi|27463074|gb|AAO15696.1...
162.0 [0..7] [132..4036]
gi|47227548 - gi|47227548|emb|CAG04696.1| unnamed protein product [Tetraodon nigroviridis]
159.0 [0..25] [167..1359]
gi|124486855, gi... - gi|82917259|ref|XP_890829.1| PREDICTED: fat tumor suppressor homolog isoform 1 [Mus musculus], gi|82...
152.0 [0..21] [170..3993]
gi|114568425 - gi|114568425|ref|XP_514061.2| PREDICTED: hemicentin 1 [Pan troglodytes]
149.0 [0..1] [170..5125]
gi|109474969 - gi|109474969|ref|XP_001065678.1| PREDICTED: similar to sushi, von Willebrand factor type A, EGF and ...
149.0 [0..5] [170..1247]

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Predicted Domain #1
Region A:
Residues: [1-171]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGYFSSSVVL LVAISSAFEF GPVAGRDLAI RDNSIWDQKE PAVRDRSFQF VPSVGIQNSK  60
   61 SLNKTCCLNG GTCILGSFCA CPPSFYGRNC EHDVRKEHCG SILHGTWLPK KCSLCRCWHG 120
  121 QLHCLPQTFL PGCDGHVMDQ DLKASRTPCQ TPSVTTTFML AGACLFLDMK V

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.522879
Match: 1n7dA
Description: Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ErbB-2 class receptor binding 6.03999755532215 bayes_pls_golite062009
growth factor activity 4.72461268561406 bayes_pls_golite062009
receptor binding 4.33045214660893 bayes_pls_golite062009
glycosaminoglycan binding 3.49243532917035 bayes_pls_golite062009
heparin binding 3.18889412817519 bayes_pls_golite062009
transcription regulator activity 3.10404768355447 bayes_pls_golite062009
protein binding 3.02592228806142 bayes_pls_golite062009
binding 2.97929690141955 bayes_pls_golite062009
ErbB-3 class receptor binding 2.81761382193046 bayes_pls_golite062009
polysaccharide binding 2.79319890241656 bayes_pls_golite062009
transcription factor binding 2.07092884468733 bayes_pls_golite062009
transcription cofactor activity 1.96338152927981 bayes_pls_golite062009
protein kinase activity 1.77969944626081 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.46474396447414 bayes_pls_golite062009
epidermal growth factor receptor binding 1.45792086043869 bayes_pls_golite062009
pattern binding 1.40261567769805 bayes_pls_golite062009
kinase activity 1.38993132583838 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.36604280237149 bayes_pls_golite062009
glycoprotein binding 1.26303225185938 bayes_pls_golite062009
signal transducer activity 1.21257866727 bayes_pls_golite062009
molecular transducer activity 1.21257866727 bayes_pls_golite062009
MAP kinase kinase activity 0.856364436331474 bayes_pls_golite062009
cell adhesion molecule binding 0.44857826904729 bayes_pls_golite062009
carbohydrate binding 0.37481112933019 bayes_pls_golite062009

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