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View Structure Prediction Details

Protein: FCF1_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 192 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FCF1_SCHPO.

Description E-value Query
Range
Subject
Range
gi|28207891 - gi|28207891|emb|CAD62599.1| unnamed protein product [Homo sapiens]
281.0 [0..1] [189..5]
gi|112984540, gi... - gi|95102022|dbj|BAE94255.1| ZH10 [Rattus norvegicus], gi|92014062|emb|CAJ88856.1| ZH10 protein [Ratt...
278.0 [0..1] [189..1]
FCF1_MOUSE - rRNA-processing protein FCF1 homolog OS=Mus musculus GN=Fcf1 PE=2 SV=2
278.0 [0..1] [189..1]
gi|149737518 - gi|149737518|ref|XP_001491026.1| PREDICTED: similar to rRNA-processing protein FCF1 homolog [Equus c...
gi|73963615 - gi|73963615|ref|XP_537508.2| PREDICTED: similar to Protein C14orf111 isoform 1 [Canis familiaris]
278.0 [0..1] [189..1]
gi|50748490 - gi|50748490|ref|XP_421270.1| PREDICTED: hypothetical protein [Gallus gallus]
275.0 [0..1] [189..1]
gi|20197374, gi|... - gi|20197374|gb|AAC62883.2| expressed protein [Arabidopsis thaliana], gi|18407014|ref|NP_566068.1| un...
274.0 [0..1] [189..1]
gi|52345910, gi|... - gi|52345910|ref|NP_001004999.1| MGC89599 protein [Xenopus (Silurana) tropicalis], gi|49522628|gb|AAH...
271.0 [0..1] [189..1]

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Predicted Domain #1
Region A:
Residues: [1-192]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKAKTTRKF AQVKRVINLK DQRLQKKDQK KEKEKTTKNG ELVREIPQMA SNLFFQFNES  60
   61 LGPPYHVIID TNFINFCLQQ KIDLFEGLMT CLYAKTIPCI SDCVMAELEK LGIRYRIALR 120
  121 IAKDERFERL PCTHKGTYAD DCIVQRVMQH KCYLVATNDK NLKQRIRKIP GIPILSVANH 180
  181 KIRVERLVDV VD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.522879
Match: 1o4wA
Description: Hypothetical protein AF0591
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nuclease activity 2.9643999717473 bayes_pls_golite062009
exonuclease activity 2.73966722455965 bayes_pls_golite062009
endodeoxyribonuclease activity 2.32240591300465 bayes_pls_golite062009
deoxyribonuclease activity 2.20319910135606 bayes_pls_golite062009
DNA binding 2.08813762501061 bayes_pls_golite062009
nucleic acid binding 1.94354032094901 bayes_pls_golite062009
flap endonuclease activity 1.93047867791632 bayes_pls_golite062009
endonuclease activity 1.76157945742159 bayes_pls_golite062009
5'-3' exonuclease activity 1.66809858159343 bayes_pls_golite062009
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1.5104333947608 bayes_pls_golite062009
binding 1.47549397931841 bayes_pls_golite062009
catalytic activity 1.37534898662234 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1.24621366977274 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.0761952249864 bayes_pls_golite062009
hydrolase activity 1.02738194339641 bayes_pls_golite062009
exodeoxyribonuclease activity, producing 5'-phosphomonoesters 0.756864776606945 bayes_pls_golite062009
exodeoxyribonuclease activity 0.74826759322705 bayes_pls_golite062009
3'-5' exonuclease activity 0.50487165366129 bayes_pls_golite062009
5'-3' exodeoxyribonuclease activity 0.34527101309477 bayes_pls_golite062009
protein binding 0.257628793674867 bayes_pls_golite062009
double-stranded DNA specific exodeoxyribonuclease activity 0.123105804280941 bayes_pls_golite062009
single-stranded DNA specific exodeoxyribonuclease activity 0.120278857913627 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle