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View Structure Prediction Details

Protein: gi|19115426
Organism: Schizosaccharomyces pombe 972h-
Length: 258 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|19115426.

Description E-value Query
Range
Subject
Range
PNO1_RAT - RNA-binding protein PNO1 OS=Rattus norvegicus GN=Pno1 PE=2 SV=1
210.0 [0..11] [257..4]
PNO1_MOUSE - RNA-binding protein PNO1 OS=Mus musculus GN=Pno1 PE=1 SV=1
209.0 [0..11] [257..4]
PNO1_GIBZE - Pre-rRNA-processing protein PNO1 OS=Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL ...
PNO1_GIBZE - Pre-rRNA-processing protein PNO1 OS=Gibberella zeae GN=PNO1 PE=3 SV=1
209.0 [0..1] [257..1]
PNO1_EMENI - Pre-rRNA-processing protein pno1 OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / ...
PNO1_EMENI - Pre-rRNA-processing protein pno1 OS=Emericella nidulans GN=pno1 PE=3 SV=1
205.0 [0..1] [257..1]
PNO1_BOVIN - RNA-binding protein PNO1 OS=Bos taurus GN=PNO1 PE=2 SV=1
205.0 [0..17] [257..6]
gi|62897797 - gi|62897797|dbj|BAD96838.1| putatative 28 kDa protein variant [Homo sapiens]
204.0 [0..11] [257..4]
gi|41351456 - gi|41351456|gb|AAH65596.1| Partner of NOB1 homolog (S. cerevisiae) [Danio rerio]
204.0 [0..23] [257..4]
gi|73969846 - gi|73969846|ref|XP_531853.2| PREDICTED: similar to putatative 28 kDa protein isoform 1 [Canis famili...
202.0 [0..1] [257..1]

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Predicted Domain #1
Region A:
Residues: [1-67]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLAPTAAVNV TNEGENGMFS PKFSLNYSLT TVSDNVMIDT TRGEIEFSDS AVNGTMDIEG  60
   61 APKFAPA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.607 b.1.2 Fibronectin type III
View Download 0.657 g.17.1 Cystine-knot cytokines
View Download 0.606 d.129.1 TATA-box binding protein-like
View Download 0.600 d.17.1 Cystatin/monellin
View Download 0.587 c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain

Predicted Domain #2
Region A:
Residues: [68-258]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTSAEKKRGA KPQMRRVPIP PHRMTPLRNV WPKLYPPLVE HLLLQVRMNT KSRSVELRES  60
   61 KATKDPGALQ KGMDFVQAFA LGFDIDDAIA LLRLDDLYID TFEIKDVKTL QGDHLSRAIG 120
  121 RIAGQGGKTK FAIENASRTR IVLADSKIHI LGGFTNIRIA KDAVVSLILG SPPGKVYANL 180
  181 RNAAARAKER I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.39794
Match: 1tuaA
Description: Structural genomics, 1.5A crystal structure of a hypothetical protein APE0754 from Aeropyrum pernix
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 4.49437316734899 bayes_pls_golite062009
nucleic acid binding 3.68444148122352 bayes_pls_golite062009
binding 2.8667878224392 bayes_pls_golite062009
mRNA binding 2.83121485081867 bayes_pls_golite062009
protein binding 1.56382009529204 bayes_pls_golite062009
transcription regulator activity 1.43703138180882 bayes_pls_golite062009
DNA binding 1.20852534725468 bayes_pls_golite062009
0.559294837259864 bayes_pls_golite062009
transcription factor activity 0.386248501195543 bayes_pls_golite062009
structure-specific DNA binding 0.32222928997178 bayes_pls_golite062009
catalytic activity 0.113112541746059 bayes_pls_golite062009
single-stranded DNA binding 0.1069917291606 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle