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View Structure Prediction Details

Protein: COX4_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 164 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COX4_SCHPO.

Description E-value Query
Range
Subject
Range
COX4_YEAST - Cytochrome c oxidase subunit 4, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288...
gi|190407127 - gi|190407127|gb|EDV10394.1| cytochrome c oxidase subunit IV [Saccharomyces cerevisiae RM11-1a]
gi|151943629 - gi|151943629|gb|EDN61939.1| cytochrome c oxidase subunit IV [Saccharomyces cerevisiae YJM789]
COX4 - Subunit IV of cytochrome c oxidase, the terminal member of the mitochondrial inner membrane electron...
238.0 [0..12] [164..4]
gi|44984721, gi|... - gi|45198711|ref|NP_985740.1| AFR193Wp [Ashbya gossypii ATCC 10895], gi|44984721|gb|AAS53564.1| AFR19...
gi|44984721 - gi|44984721|gb|AAS53564.1| AFR193Wp [Ashbya gossypii ATCC 10895]
219.0 [0..12] [164..4]
gi|50293263, gi|... - gi|50293263|ref|XP_449043.1| unnamed protein product [Candida glabrata], gi|49528356|emb|CAG62013.1|...
gi|49528356|emb|... - unnamed protein product [Candida glabrata CBS 138]
211.0 [0..1] [164..1]
gi|68466934, gi|... - gi|68466934|ref|XP_722382.1| hypothetical protein CaO19.9046 [Candida albicans SC5314], gi|68466651|...
orf19.9046, orf1... - COX4 CGDID:CAL0004689 Assembly 19, Contig19-10119 (52934, 53407) CDS, translated using codon table 1...
208.0 [0..1] [163..1]
gi|39973437, gi|... - gi|39973437|ref|XP_368109.1| hypothetical protein MG01135.4 [Magnaporthe grisea 70-15], gb|EAA49477....
206.0 [0..1] [158..31]
gi|67536710, gi|... - gi|67536710|ref|XP_662129.1| hypothetical protein AN4525.2 [Aspergillus nidulans FGSC A4], ref|XP_40...
201.0 [0..2] [158..3]
COX4_NEUCR - Cytochrome c oxidase subunit 4, mitochondrial OS=Neurospora crassa GN=cox-4 PE=3 SV=2
COX4_NEUCR - Cytochrome c oxidase subunit 4, mitochondrial OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A /...
199.0 [0..25] [157..23]
gi|50306625, gi|... - gi|50306625|ref|XP_453286.1| unnamed protein product [Kluyveromyces lactis], gi|49642420|emb|CAH0038...
gi|49642420 - gi|49642420|emb|CAH00382.1| KLLA0D05082p [Kluyveromyces lactis]
196.0 [0..6] [163..1]
gi|88181275, gi|... - gi|88181275|gb|EAQ88743.1| hypothetical protein CHGG_05362 [Chaetomium globosum CBS 148.51], gi|1161...
193.0 [0..24] [164..23]
gi|46111661, gi|... - gi|46111661|ref|XP_382888.1| hypothetical protein FG02712.1 [Gibberella zeae PH-1], gi|42545117|gb|E...
191.0 [0..9] [156..462]

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Predicted Domain #1
Region A:
Residues: [1-164]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFMNSMLRVS RQRAAVRSTV SLYRGFVSAS IRRNEQNVVK AAAQELANAK EPSDLIGPGG  60
   61 RDGEVPTDLE QATGLERYEL LSELSGRDAF DMKPLDASRK GTLTDPIMVT SLDPYRHIGC 120
  121 TGSPSGSHNL IWMTVYKDKL RRCPECGSVY KLKFMGDPNA EHSH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.39794
Match: 1occF
Description: Cytochrome c oxidase Subunit F
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytochrome-c oxidase activity 11.8078336041861 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors 11.8078336041861 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor 11.8078336041861 bayes_pls_golite062009
heme-copper terminal oxidase activity 11.4955994709345 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 5.35533851539468 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 5.20400060522221 bayes_pls_golite062009
electron carrier activity 4.79439258177657 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 4.61075334342911 bayes_pls_golite062009
oxidoreductase activity 4.60275002826443 bayes_pls_golite062009
cation transmembrane transporter activity 4.37169157675849 bayes_pls_golite062009
ion transmembrane transporter activity 4.17914534558054 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.78062052867494 bayes_pls_golite062009
substrate-specific transporter activity 3.5925267150231 bayes_pls_golite062009
binding 1.8195473608185 bayes_pls_golite062009
catalytic activity 0.176396048613815 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle