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View Structure Prediction Details

Protein: RAD22_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 469 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RAD22_SCHPO.

Description E-value Query
Range
Subject
Range
gi|542221, gi|397583 - pir||S41496 rad22 protein - fission yeast (Schizosaccharomyces pombe), gi|397583|emb|CAA51021.1| rad...
468.0 [0..1] [469..1]
gi|46432572, gi|... - gi|68489841|ref|XP_711260.1| potential dsDNA break repair annealing factor [Candida albicans SC5314]...
orf19.4208, orf1... - RAD52 CGDID:CAL0000064 Assembly 19, Contig19-10201 (22122, 23816) CDS, translated using codon table ...
316.0 [0..20] [457..62]
gi|39946630, gi|... - gi|39946630|ref|XP_362852.1| hypothetical protein MG08585.4 [Magnaporthe grisea 70-15], gb|EAA49670....
313.0 [0..4] [467..78]
gi|109474108 - gi|109474108|ref|XP_001057419.1| PREDICTED: similar to RAD52 homolog [Rattus norvegicus]
296.0 [0..18] [317..29]
gi|17512302 - gi|17512302|gb|AAH19123.1| Rad52 protein [Mus musculus]
296.0 [0..18] [305..29]
gi|23200258, gi|... - gi|23200266|pdb|1KN0|K Chain K, Crystal Structure Of The Human Rad52 Protein, gi|23200265|pdb|1KN0|J...
295.0 [0..18] [203..28]
RAD52_MAGO7 - DNA repair and recombination protein rhm52 OS=Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGS...
RAD52_MAGGR, RA5... - DNA repair and recombination protein rhm52 OS=Magnaporthe grisea GN=RHM52 PE=2 SV=1, (Q8NK72) DNA re...
295.0 [0..4] [467..6]
gi|73997819 - gi|73997819|ref|XP_534926.2| PREDICTED: similar to DNA repair protein RAD52 homolog [Canis familiari...
287.0 [0..18] [249..28]

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Predicted Domain #1
Region A:
Residues: [1-203]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFEQKQHVA SEDQGHFNTA YSHEEFNFLQ SSLTRKLGPE YVSRRSGPGG FSVSYIESWK  60
   61 AIELANEIFG FNGWSSSIRS INVDFMDENK ENGRISLGLS VIVRVTIKDG AYHEDIGYGS 120
  121 IDNCRGKASA FEKCKKEGTT DALKRALRNF GNSLGNCMYD KYYLREVGKM KPPTYHFDSG 180
  181 DLFRKTDPAA RESFIKKQKT LNS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 80.0
Match: 1kn0A
Description: The homologous-pairing domain of Rad52 recombinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 3.14765341131293 bayes_pls_golite062009
nucleic acid binding 3.0351747710117 bayes_pls_golite062009
RNA binding 1.51047378734681 bayes_pls_golite062009
protein binding 1.45612186272752 bayes_pls_golite062009
DNA binding 1.36164279504822 bayes_pls_golite062009
transcription regulator activity 1.01871957569312 bayes_pls_golite062009
double-stranded RNA binding 0.486416546047936 bayes_pls_golite062009
transcription factor activity 0.1846534408189 bayes_pls_golite062009
structure-specific DNA binding 0.109630981204183 bayes_pls_golite062009
structural constituent of ribosome 0.0240483444006283 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [204-322]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TRTVNNQPLV NKGEQLAPRR AAELNDEQTR EIEMYADEEL DNIFVEDDII AHLAVAEDTA  60
   61 HPAANNHHSE KAGTQINNKD KGSHNSAKPV QRSHTYPVAV PQNTSDSVGN AVTDTSPKT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [323-469]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LFDPLKPNTG TPSPKFISAR AAAAAEGVVS APFTNNFNPR LDSPSIRKTS IIDHSKSLPV  60
   61 QRASVLPIIK QSSQTSPVSN NSMIRDSESI INERKENIGL IGVKRSLHDS TTSHNKSDLM 120
  121 RTNSDPQSAM RSRENYDATV DKKAKKG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle