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View Structure Prediction Details

Protein: gi|109124583
Organism: Macaca mulatta
Length: 218 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|109124583.

Description E-value Query
Range		 Subject
Range
gi|5114051 - gi|5114051|gb|AAD40193.1| HSPC029 [Homo sapiens]
 0.0 [1..218] [1..218]
tr|M3WUN8|M3WUN8... - Eukaryotic translation initiation factor 3 subunit K OS=Felis catus GN=EIF3K PE=3 SV=1
EIF3K_BOVIN - Eukaryotic translation initiation factor 3 subunit K OS=Bos taurus GN=EIF3K PE=2 SV=1
gi|149722101 - gi|149722101|ref|XP_001497262.1| PREDICTED: similar to eukaryotic translation initiation factor 3, s...
gi|57036583 - gi|57036583|ref|XP_533679.1| PREDICTED: similar to eukaryotic translation initiation factor 3, subun...
 0.0 [1..218] [1..218]
EIF3K_MOUSE - Eukaryotic translation initiation factor 3 subunit K OS=Mus musculus GN=Eif3k PE=1 SV=1
 0.0 [1..218] [1..218]
gi|149056429, gi... - gi|27730981|ref|XP_214886.1| PREDICTED: similar to eukaryotic translation initiation factor 3, subun...
 0.0 [1..218] [1..218]
EIF3K_XENLA - Eukaryotic translation initiation factor 3 subunit K OS=Xenopus laevis GN=eif3k PE=2 SV=1
 1.0E-99 [1..218] [1..218]
EIF3K_XENTR - Eukaryotic translation initiation factor 3 subunit K OS=Xenopus tropicalis GN=eif3k PE=2 SV=1
 4.0E-99 [1..218] [1..218]
EIF3K_DANRE - Eukaryotic translation initiation factor 3 subunit K OS=Danio rerio GN=eif3k PE=2 SV=1
 8.0E-92 [2..218] [3..219]
gi|47208549 - gi|47208549|emb|CAF95696.1| unnamed protein product [Tetraodon nigroviridis]
 2.0E-91 [1..218] [1..218]

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Predicted Domain #1
Region A:
Residues: [1-218] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMFEQMRAN VGKLLKGIDR YNPENLATLE RYVETQAKEN AYDLEANLAV LKLYQFNPAF  60
   61 FQTTVTAQIL LKALTNLPHT DFTLCKCMID QAHQEERPIR QILYLGDLLE TCHFQAFWQA 120
  121 LDENMDLLEG ITGFEDSVRK FICHVVGITY QHIDRWLLAE MLGDLSDSQL KVWMSKYGWS 180
  181 ADESGQIFIC SQEESIKPKN IVEKIDFDSV SSIMASSQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 109.0
Match: 1rz4A
Description: Crystal Structure of Human eIF3k
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
translation initiation factor activity 4.65136805471804 bayes_pls_golite062009
binding 2.27902748675387 bayes_pls_golite062009
protein binding 1.94427330399472 bayes_pls_golite062009
RNA cap binding 1.73309326409609 bayes_pls_golite062009
sequence-specific DNA binding 0.93130370844712 bayes_pls_golite062009
structural molecule activity 0.908029258648777 bayes_pls_golite062009
nucleic acid binding 0.856241051862415 bayes_pls_golite062009
translation regulator activity 0.82193201542158 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.803700928110921 bayes_pls_golite062009
structural constituent of ribosome 0.742648546865457 bayes_pls_golite062009
transcription repressor activity 0.67795138236883 bayes_pls_golite062009
RNA binding 0.39193569533369 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.10854873707001 bayes_pls_golite062009
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