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View Structure Prediction Details

Protein: gi|109097588
Organism: Macaca mulatta
Length: 981 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|109097588.

Description E-value Query
Range
Subject
Range
gi|73968609 - gi|73968609|ref|XP_849935.1| PREDICTED: similar to Ubiquitin carboxyl-terminal hydrolase 15 (Ubiquit...
0.0 [1..981] [1..981]
gi|53759136 - gi|53759136|ref|NP_990171.2| ubiquitin specific peptidase 15 isoform 1 [Gallus gallus]
0.0 [1..981] [1..981]
gi|114644046 - gi|114644046|ref|XP_509182.2| PREDICTED: ubiquitin specific protease 15 isoform 6 [Pan troglodytes]
0.0 [1..981] [1..981]
UBP15_MOUSE - Ubiquitin carboxyl-terminal hydrolase 15 OS=Mus musculus GN=Usp15 PE=1 SV=1
0.0 [1..981] [1..981]
gi|109097590 - gi|109097590|ref|XP_001116737.1| PREDICTED: ubiquitin specific peptidase 15 isoform 2 [Macaca mulatt...
gi|168267398 - gi|168267398|dbj|BAG09755.1| ubiquitin carboxyl-terminal hydrolase 15 [synthetic construct]
gi|119617512, gi... - gi|5814097|gb|AAD52099.1|AF106069_1 deubiquitinating enzyme [Homo sapiens], gi|20521071|dbj|BAA25455...
0.0 [1..981] [1..952]

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Predicted Domain #1
Region A:
Residues: [1-120]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEGGAADLD TQRSDIATLL KTSLRKGDTW YLVDSRWFKQ WKKYVGFDSW DKYQMGDQNV  60
   61 YPGPIDNSGL LKDGDAQSLK EHLIDELDYI LLPTEGWNKL VSWYTLMEGQ EPIARKVVEQ 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.0
Match: 1w6vA
Description: Solution structure of the DUSP domain of hUSP15
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [121-225]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GMFVKHCKVE VYLTELKLCE NGNMNNVVTR RFSKADTIDT IEKEIRKIFS IPDEKETRLW  60
   61 NKYMSNTFEP LNKPDSTIQD AGLYQGQVLV IEQKNEDGTW PRGPS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.39
Match: 1v5oA
Description: Solution Structure of the Ubiquitin-like Domain from Mouse Hypothetical 1700011N24Rik Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.11588141989606 bayes_pls_golite062009
hydrolase activity 1.71270780201188 bayes_pls_golite062009
small conjugating protein ligase activity 1.64626529520014 bayes_pls_golite062009
ubiquitin-protein ligase activity 1.03640529353043 bayes_pls_golite062009
protein binding 1.03325409251792 bayes_pls_golite062009
acid-amino acid ligase activity 0.778769490362734 bayes_pls_golite062009
nucleic acid binding 0.406724367405638 bayes_pls_golite062009
DNA binding 0.102021710653816 bayes_pls_golite062009
transcription regulator activity 0.0672274772804511 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [226-572]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPKSPGASNF STLPKISPSS LSNNYNNMNN RNVKNSNYCL PSYTAYKNYD YSEPGRNNEQ  60
   61 PGLCGLSNLG NTCFMNSAIQ CLSNTPPLTE YFLNDKYQEE LNFDNPLGMR GEIAKSYAEL 120
  121 IKQMWSGKFS YVTPRAFKTQ VGRFAPQFSG YQQQDCQELL AFLLDGLHED LNRIRKKPYI 180
  181 QLKDADGRPD KVVAEEAWEN HLKRNDSIIV DIFHGLFKST LVCPECAKIS VTFDPFCYLT 240
  241 LPLPMKKERT LEVYLVRMDP LTKPMQYKVV VPKIGNILDL CTALSALSGI PADKMIVTDI 300
  301 YNHRFHRIFA MDENLSSIME RDDIYVFEIN INRTEDTEHV IIPVCLR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 65.221849
Match: 2gfoA
Description: No description for 2gfoA was found.

Predicted Domain #4
Region A:
Residues: [573-981]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKFRHSSYTH HTGSSLFGQP FLMAVPRNNT EDKLYNLLLL RMCRYVKIST ETEETEGSLH  60
   61 CCKDQNINGN GPNGIHEEGS PSEMETDEPD DESSQDQELP SENENSQSED SVGGDNDSEN 120
  121 GLCTEDTCKG QLTGHKKRLF TFQFNNLGNT DINYIKDDTR HIRFDDRQLR LDERSFLALD 180
  181 WDPDLKKRYF DENAAEDFEK HESVEYKPPK KPFVKLKDCI ELFTTKEKLG AEDPWYCPNC 240
  241 KEHQQATKKL DLWSLPPVLV VHLKRFSYSR YMRDKLDTLV DFPINDLDMS EFLINPNAGP 300
  301 CRYNLIAVSN HYGGMGGGHY TAFAKNKDDG KWYYFDDSSV STASEDQIVS KAAYVLFYQR 360
  361 QDTFSGTGFF PLDRETKGAS AATGIPLESD EDSNDNDNDI ENENCMHTN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.39794
Match: 2f1zA
Description: Crystal structure of HAUSP
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle