YRC Public Data Repository - Protein Structure Prediction

Protein:	BETI_YERPN
Organism:	Yersinia pestis Nepal516
Length:	198 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BETI_YERPN.

Description	E-value	Query Range	Subject Range
gi\|94498978, gi\|... - gi\|94498978\|ref\|ZP_01305516.1\| Transcriptional regulator [Oceanobacter sp. RED65], gi\|94428610\|gb\|EA...	2.0E-25	[1..190]	[1..190]
gi\|23097975, gi\|... - gi\|23097975\|ref\|NP_691441.1\| transcriptional regulator [Oceanobacillus iheyensis HTE831], gi\|2277619...	3.0E-25	[1..194]	[1..201]
gi\|45440827, gi\|... - gi\|45440827\|ref\|NP_992366.1\| transcriptional regulator BetI [Yersinia pestis biovar Microtus str. 91...	2.0E-24	[2..198]	[10..206]
gi\|84386107, gi\|... - gi\|84386107\|ref\|ZP_00989136.1\| transcriptional regulator BetI [Vibrio splendidus 12B01], gi\|84378877...	5.0E-24	[1..195]	[1..195]
gi\|28202287, gi\|... - gi\|28209852\|ref\|NP_780796.1\| TetR family transcriptional regulator [Clostridium tetani E88], gi\|2820...	9.0E-24	[9..192]	[3..186]
gi\|75702427, gi\|... - gi\|75908702\|ref\|YP_322998.1\| TetR family transcriptional regulator [Anabaena variabilis ATCC 29413],...	1.0E-23	[5..195]	[2..198]
gi\|88799551, gi\|... - gi\|88799551\|ref\|ZP_01115127.1\| Transcriptional regulator [Reinekea sp. MED297], gi\|88777636\|gb\|EAR08...	2.0E-23	[1..192]	[1..192]
gi\|36787146, gi\|... - gi\|37527710\|ref\|NP_931055.1\| DNA-binding transcriptional repressor AcrR [Photorhabdus luminescens su...	6.0E-23	[1..191]	[1..202]
gi\|86144744, gi\|... - gi\|86144744\|ref\|ZP_01063076.1\| transcriptional regulator BetI [Vibrio sp. MED222], gi\|85837643\|gb\|EA...	7.0E-23	[1..195]	[1..195]
gi\|25534034 - pir\|\|AG2376 transcription regulator alr4567 [imported] - Nostoc sp. (strain PCC 7120) gi\|17232059, gi\|... - gi\|17232059\|ref\|NP_488607.1\| transcriptional regulator [Nostoc sp. PCC 7120], gi\|17133703\|dbj\|BAB762...	7.0E-23	[5..193]	[2..196]

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Predicted Domain #1

Region A:
Residues: [1-198]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKVGMQPIR RQQLIEATMA AVNEVGMHEA SIAQIAKRAG VSNGIISHYF RDKNGLLEAT  60
   61 MRYLIRHLGE AVKQHLAALS VNDPRARLRA IAEGNFDDSQ INSAAMKTWL AFWASSMHSP 120
  121 QLYRLQQVNN RRLYSNLCAE FKRCLPREQA QLAAKGMAGL IDGLWLRSAL SGEHFNRQEA 180
  181 LLIIHNYIEQ QLNIKYKC

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.522879
Match:	1vi0A
Description:	Crystal structure of a transcriptional regulator
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	4.29755359385997	bayes_pls_golite062009
DNA binding	3.01268207226307	bayes_pls_golite062009
transcription factor activity	3.00408040212712	bayes_pls_golite062009
nucleic acid binding	2.9430921064275	bayes_pls_golite062009
binding	1.69234246404005	bayes_pls_golite062009
sequence-specific DNA binding	0.46503550280898	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.24108783215685	bayes_pls_golite062009
protein binding	0.111941607625758	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: