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View Structure Prediction Details

Protein: RNAS4_MOUSE
Organism: Mus musculus
Length: 148 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RNAS4_MOUSE.

Description E-value Query
Range
Subject
Range
gi|26344600, gi|... - gi|31981520|ref|NP_035401.2| pancreatic ribonuclease [Mus musculus], gi|26344600|dbj|BAC35949.1| unn...
231.0 [0..2] [147..1]
RNAS1_MUSSA - Ribonuclease pancreatic OS=Mus saxicola GN=Rnase1 PE=2 SV=1
229.0 [0..2] [147..1]
RNS1A_RATEX - Ribonuclease pancreatic alpha-type OS=Rattus exulans PE=3 SV=1
228.0 [0..2] [147..1]
gi|18376502 - gi|18376502|emb|CAC86435.1| pancreatic ribonuclease alpha [Berylmys bowersi]
228.0 [0..2] [147..1]
RNAS1_URARU - Ribonuclease pancreatic OS=Uranomys ruddi GN=RNASE1 PE=2 SV=1
224.0 [0..2] [147..1]
RNAS1_NIVCR - Ribonuclease pancreatic OS=Niviventer cremoriventer GN=RNASE1 PE=2 SV=1
222.0 [0..2] [147..1]
RNAS1_MUSPA - Ribonuclease pancreatic OS=Mus pahari GN=Rnase1 PE=2 SV=1
222.0 [0..2] [147..1]
RNS1A_RATFU - Ribonuclease pancreatic alpha-type OS=Rattus fuscipes PE=3 SV=1
222.0 [0..2] [147..1]
RNAS1_LEOED, RNP... - (Q9WUS3) Ribonuclease pancreatic precursor (EC 3.1.27.5) (RNase 1) (RNase A), (Q9WUS3) Ribonuclease ...
RNAS1_LEOED - Ribonuclease pancreatic OS=Leopoldamys edwardsi GN=RNASE1 PE=2 SV=1
221.0 [0..2] [147..1]

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Predicted Domain #1
Region A:
Residues: [1-148]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMDLQRTQSL LLLLVLTLLG LGLVQPSYGQ DRMYQRFLRQ HVDPQATGGN DNYCNVMMQR  60
   61 RKMTSVQCKR FNTFIHEDIW NIRGICSTTN ILCKNGQMNC HEGVVKVTDC RETGNSKAPN 120
  121 CRYRARTSTR RVVIACEGDP EVPVHFDR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.69897
Match: 1rnfA
Description: Ribonuclease 4
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
copper ion binding 7.83873950118271 bayes_pls_golite062009
ribonuclease activity 7.7836205160091 bayes_pls_golite062009
glycosaminoglycan binding 5.76187095683544 bayes_pls_golite062009
heparin binding 5.47129826629317 bayes_pls_golite062009
polysaccharide binding 5.05032546822599 bayes_pls_golite062009
actin binding 4.92941980452441 bayes_pls_golite062009
cytoskeletal protein binding 4.36902055736911 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 4.32374837032673 bayes_pls_golite062009
receptor binding 3.75411703515817 bayes_pls_golite062009
pattern binding 3.51086739633778 bayes_pls_golite062009
nuclease activity 3.07697924678131 bayes_pls_golite062009
carbohydrate binding 2.53927247892334 bayes_pls_golite062009
binding 2.456168052491 bayes_pls_golite062009
RNA binding 2.36041337585723 bayes_pls_golite062009
protein binding 2.18342402068792 bayes_pls_golite062009
nucleic acid binding 2.03519718891127 bayes_pls_golite062009
hydrolase activity 1.87908884191558 bayes_pls_golite062009
DNA binding 1.74627208866206 bayes_pls_golite062009
transition metal ion binding 1.7277182307311 bayes_pls_golite062009
catalytic activity 1.25983854650131 bayes_pls_golite062009
cation binding 0.818478047973828 bayes_pls_golite062009
metal ion binding 0.818478047973828 bayes_pls_golite062009
ion binding 0.811382627786056 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle