YRC Public Data Repository - Protein Structure Prediction

Protein:	CNOT7_MOUSE
Organism:	Mus musculus
Length:	285 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CNOT7_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|149742664, gi... - gi\|149742664\|ref\|XP_001488485.1\| PREDICTED: similar to CNOT7 protein isoform 1 [Equus caballus], gi\|... CCDS6000.2_1 - null CNOT7_CHICK - CCR4-NOT transcription complex subunit 7 OS=Gallus gallus GN=CNOT7 PE=2 SV=1 gi\|73979407 - gi\|73979407\|ref\|XP_540010.2\| PREDICTED: similar to CCR4-NOT transcription complex subunit 7 (CCR4-as... gi\|109085706, gi... - gi\|109085706\|ref\|XP_001095793.1\| PREDICTED: CCR4-NOT transcription complex, subunit 7 isoform 7 [Mac... gi\|114618908, gi... - gi\|114618908\|ref\|XP_001141414.1\| PREDICTED: hypothetical protein LOC464006 isoform 2 [Pan troglodyte... ENSCJAT00000022924 - null tr\|M3VV22\|M3VV22... - CCR4-NOT transcription complex subunit 7 OS=Felis catus GN=CNOT7 PE=4 SV=1 gi\|542149998\|ref... - PREDICTED: CCR4-NOT transcription complex subunit 7 [Zonotrichia albicollis] gi\|224049852 - gi\|224049852\|ref\|XP_002194151.1\| PREDICTED: CCR4-NOT transcription complex, subunit 7 [Taeniopygia g... CNOT7 - CCR4-NOT transcription complex, subunit 7 tr\|G3GZC4\|G3GZC4... - CCR4-NOT transcription complex subunit 7 OS=Cricetulus griseus GN=H671_1g2546 PE=4 SV=1 tr\|G1T7P8\|G1T7P8... - pep:novel scaffold:oryCun2:GL018717:2257628:2258485:-1 gene:ENSOCUG00000023781 transcript:ENSOCUT000...	454.0	[0..1]	[285..1]
gi\|33150534 - gi\|33150534\|gb\|AAP97145.1\|AF086915_1 CAF1 [Homo sapiens]	453.0	[0..1]	[285..1]
gi\|74204962 - gi\|74204962\|dbj\|BAE20968.1\| unnamed protein product [Mus musculus]	450.0	[0..1]	[285..1]
gi\|114594537 - gi\|114594537\|ref\|XP_001164866.1\| PREDICTED: similar to CCR4-NOT transcription complex, subunit 7 iso...	447.0	[0..1]	[285..1]
CNOT7_XENLA - CCR4-NOT transcription complex subunit 7 OS=Xenopus laevis GN=cnot7 PE=1 SV=1	447.0	[0..1]	[285..1]
CNOT7_DANRE - CCR4-NOT transcription complex subunit 7 OS=Danio rerio GN=cnot7 PE=2 SV=1	443.0	[0..1]	[284..1]
gi\|47221370 - gi\|47221370\|emb\|CAF97288.1\| unnamed protein product [Tetraodon nigroviridis]	434.0	[0..1]	[284..1]

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Predicted Domain #1

Region A:
Residues: [1-285]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPAATVDHSQ RICEVWACNL DEEMKKIRQV IRKYNYVAMD TEFPGVVARP IGEFRSNADY  60
   61 QYQLLRCNVD LLKIIQLGLT FMNEQGEYPP GTSTWQFNFK FNLTEDMYAQ DSIELLTTSG 120
  121 IQFKKHEEEG IETQYFAELL MTSGVVLCEG VKWLSFHSGY DFGYLIKILT NSNLPEEELD 180
  181 FFEILRLFFP VIYDVKYLMK SCKNLKGGLQ EVAEQLELER IGPQHQAGSD SLLTGMAFFK 240
  241 MREMFFEDHI DDAKYCGHLY GLGSGSSYVQ NGTGNAYEEE ASKQS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	115.0
Match:	2d5rA
Description:	No description for 2d5rA was found.

Predicted functions:

Term	Confidence	Notes
nuclease activity	3.11657409772275	bayes_pls_golite062009
ribonuclease activity	2.66669472409706	bayes_pls_golite062009
transcription regulator activity	2.20855917457806	bayes_pls_golite062009
nucleic acid binding	2.14285769817394	bayes_pls_golite062009
exonuclease activity	1.87925169250843	bayes_pls_golite062009
DNA binding	1.86594005896134	bayes_pls_golite062009
3'-5' exonuclease activity	1.44123900197846	bayes_pls_golite062009
transcription activator activity	1.43417601839369	bayes_pls_golite062009
exoribonuclease activity	1.41353777396851	bayes_pls_golite062009
binding	1.35497934205068	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	1.33509846387956	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	1.32513822925426	bayes_pls_golite062009
catalytic activity	1.25233849524628	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.19753926150484	bayes_pls_golite062009
transcription factor activity	1.17659544650821	bayes_pls_golite062009
protein binding	1.08578027658199	bayes_pls_golite062009
endonuclease activity	0.991569665925888	bayes_pls_golite062009
3'-5'-exoribonuclease activity	0.98331180621651	bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	0.71760273606768	bayes_pls_golite062009
endoribonuclease activity, producing 5'-phosphomonoesters	0.708753843279937	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.615788727884275	bayes_pls_golite062009
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	0.598360955770972	bayes_pls_golite062009
	0.49473250705373	bayes_pls_golite062009
deoxyribonuclease activity	0.24906263529692	bayes_pls_golite062009
DNA-directed DNA polymerase activity	0.09423425042945	bayes_pls_golite062009
DNA polymerase activity	0.0189279348688405	bayes_pls_golite062009
endoribonuclease activity	0.016619833072142	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: