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View Structure Prediction Details

Protein: CTDS1_MOUSE
Organism: Mus musculus
Length: 261 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CTDS1_MOUSE.

Description E-value Query
Range
Subject
Range
gi|109487310, gi... - gi|62655202|ref|XP_343589.2| PREDICTED: similar to Carboxy-terminal domain RNA polymerase II polypep...
324.0 [0..1] [261..1]
CTDSP1 - CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
gi|208966090, gi... - gi|208966090|dbj|BAG73059.1| CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small p...
324.0 [0..1] [261..1]
gi|109100976 - gi|109100976|ref|XP_001090300.1| PREDICTED: similar to CTD (carboxy-terminal domain, RNA polymerase ...
324.0 [0..1] [261..1]
gi|114583310 - gi|114583310|ref|XP_001156881.1| PREDICTED: CTD (carboxy-terminal domain, RNA polymerase II, polypep...
323.0 [0..1] [261..1]
gi|74005486 - gi|74005486|ref|XP_851188.1| PREDICTED: similar to CTD (carboxy-terminal domain, RNA polymerase II, ...
323.0 [0..1] [261..1]
gi|6572954 - gi|6572954|gb|AAF17482.1|AF189774_1 NLI-interacting factor isoform T2; NLI/Ldb1/CLIM interacting fac...
310.0 [0..1] [257..1]
gi|94386750 - gi|94386750|ref|XP_001001477.1| PREDICTED: similar to CTD (carboxy-terminal domain, RNA polymerase I...
307.0 [0..1] [257..1]

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Predicted Domain #1
Region A:
Residues: [1-72]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSSAVITQI SKEEARGPLR GKGDQKSAVS QKPRSRGILH SLFCCVCRDD GEPLPAHSGA  60
   61 PLLVEENGAI PK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [73-261]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HTPVQYLLPE AKAQDSDKIC VVIDLDETLV HSSFKPVNNA DFIIPVEIDG VVHQVYVLKR  60
   61 PHVDEFLQRM GELFECVLFT ASLAKYADPV ADLLDKWGAF RARLFRESCV FHRGNYVKDL 120
  121 SRLGRDLRRV LILDNSPASY VFHPDNAVPV ASWFDNMSDT ELHDLLPFFE QLSRVDDVYS 180
  181 VLRQPRPGS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 65.522879
Match: 1ta0A
Description: Three-dimensional structure of a RNA-polymerase II binding protein with associated ligand.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 1.47320207089721 bayes_pls_golite062009
catalytic activity 1.01036457072229 bayes_pls_golite062009
binding 0.94971260438956 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.361621573920296 bayes_pls_golite062009
pyrophosphatase activity 0.290412096949025 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.270489787263307 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.268673530091746 bayes_pls_golite062009
ion transmembrane transporter activity 0.138050287397444 bayes_pls_golite062009
cation transmembrane transporter activity 0.00945939738917856 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.00340058324101489 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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