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View Structure Prediction Details

Protein: GFRP_MOUSE
Organism: Mus musculus
Length: 84 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GFRP_MOUSE.

Description E-value Query
Range		 Subject
Range
gi|109080777 - gi|109080777|ref|XP_001097382.1| PREDICTED: similar to GTP cyclohydrolase I feedback regulator [Maca...
 180.0 [0..1] [84..188]
GFRP_RAT - GTP cyclohydrolase 1 feedback regulatory protein OS=Rattus norvegicus GN=Gchfr PE=1 SV=3
 178.0 [0..1] [84..1]
GFRP_BOVIN - GTP cyclohydrolase 1 feedback regulatory protein OS=Bos taurus GN=GCHFR PE=3 SV=1
 174.0 [0..1] [84..1]
GFRP_DANRE - GTP cyclohydrolase 1 feedback regulatory protein OS=Danio rerio GN=gchfr PE=3 SV=1
 172.0 [0..1] [84..1]
gi|114656407 - gi|114656407|ref|XP_001146591.1| PREDICTED: GTP cyclohydrolase I feedback regulatory protein [Pan tr...
GCHFR - GTP cyclohydrolase I feedback regulator
 171.0 [0..1] [84..1]
gi|74000128 - gi|74000128|ref|XP_544622.2| PREDICTED: similar to GTP cyclohydrolase I feedback regulator [Canis fa...
 170.0 [0..1] [84..1]
GFRP_XENTR - GTP cyclohydrolase 1 feedback regulatory protein OS=Xenopus tropicalis GN=gchfr PE=3 SV=1
 170.0 [0..1] [84..1]
gi|50747626 - gi|50747626|ref|XP_420935.1| PREDICTED: similar to RIKEN cDNA 2010323F13 gene [Gallus gallus]
 165.0 [0..1] [84..63]

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Predicted Domain #1
Region A:
Residues: [1-84] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPYLLISTQI RMEVGPTMVG DEHSDPELMQ HLGASKRSVL GNNFYEYYVN DPPRIVLDKL  60
   61 ECKGFRVLSM TGVGQTLVWC LHKE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.39794
Match: 1is7K
Description: GTP cyclohydrolase I feedback regulatory protein, GFRP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
GTP cyclohydrolase I binding 11.3014283245219 bayes_pls_golite062009
binding 2.47268310088535 bayes_pls_golite062009
amine binding 1.5114890979342 bayes_pls_golite062009
protein binding 1.15687168153762 bayes_pls_golite062009
amino acid binding 1.04261268543529 bayes_pls_golite062009
enzyme binding 0.89372263157155 bayes_pls_golite062009
enzyme inhibitor activity 0.644216978213641 bayes_pls_golite062009
GTP-dependent protein binding 0.0436251219952595 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle