YRC Public Data Repository - Protein Structure Prediction

Protein:	IMMP1L
Organism:	Homo sapiens
Length:	166 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IMMP1L.

Description	E-value	Query Range	Subject Range
gi\|186684006, gi... - gi\|23125131\|ref\|ZP_00107078.1\| COG0681: Signal peptidase I [Nostoc punctiforme PCC 73102], gi\|186684...	3.0E-43	[3..154]	[15..190]
gi\|17230467, gi\|... - gi\|17230467\|ref\|NP_487015.1\| hypothetical protein alr2975 [Nostoc sp. PCC 7120], gi\|17132069\|dbj\|BAB... gi\|25327710 - pir\|\|AH2177 hypothetical protein alr2975 [imported] - Nostoc sp. (strain PCC 7120)	3.0E-43	[3..154]	[15..190]
gi\|75700879, gi\|... - gi\|75907154\|ref\|YP_321450.1\| thylakoidal processing peptidase [Anabaena variabilis ATCC 29413], gi\|7...	8.0E-43	[3..154]	[15..190]
gi\|53762964, gi\|... - gi\|81299298\|ref\|YP_399506.1\| thylakoidal processing peptidase [Synechococcus elongatus PCC 7942], gi... gi\|56751041, gi\|... - gi\|56751041\|ref\|YP_171742.1\| signal peptidase I [Synechococcus elongatus PCC 6301], gi\|56686000\|dbj\|...	3.0E-42	[4..164]	[20..202]
gi\|83572735, gi\|... - gi\|83589821\|ref\|YP_429830.1\| signal peptidase I [Moorella thermoacetica ATCC 39073], gi\|83572735\|gb\|...	4.0E-42	[8..155]	[18..184]
gi\|46119422, gi\|... - gi\|67923384\|ref\|ZP_00516864.1\| Signal peptidase I [Crocosphaera watsonii WH 8501], gi\|67854765\|gb\|EA...	1.0E-41	[9..160]	[22..195]
gi\|76679600 - gi\|76679600\|ref\|XP_874453.1\| PREDICTED: similar to CG9240-PA [Bos taurus]	5.0E-41	[1..166]	[1..166]
gi\|149022834, gi... - gi\|149022834\|gb\|EDL79728.1\| rCG27139, isoform CRA_b [Rattus norvegicus], gi\|109470333\|ref\|XP_0010737...	6.0E-41	[1..166]	[1..166]
IMP1L_MOUSE - Mitochondrial inner membrane protease subunit 1 OS=Mus musculus GN=Immp1l PE=1 SV=1	7.0E-41	[1..166]	[1..166]
gi\|57099535 - gi\|57099535\|ref\|XP_533164.1\| PREDICTED: similar to CG9240-PA isoform 1 [Canis familiaris]	8.0E-41	[1..166]	[1..166]

Back

Predicted Domain #1

Region A:
Residues: [1-102]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRGVLGKTF RLVGYTIQYG CIAHCAFEYV GGVVMCSGPS MEPTIQNSDI VFAENLSRHF  60
   61 YGIQRGDIVI AKSPSDPKSN ICKRVIGLEG DKILTTSPSD FF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.39794
Match:	1t7dA
Description:	Crystal structure of Escherichia coli type I signal peptidase in complex with a lipopeptide inhibitor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.11782314304444	bayes_pls_golite062009
transcription regulator activity	0.792527551625403	bayes_pls_golite062009
hydrolase activity	0.665387873931151	bayes_pls_golite062009
protein binding	0.585455430771587	bayes_pls_golite062009
nucleic acid binding	0.534503048112656	bayes_pls_golite062009
peptidase activity	0.226684294251246	bayes_pls_golite062009
DNA binding	0.135756399271147	bayes_pls_golite062009
catalytic activity	0.0451617952658021	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	0.017256655639107	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [103-166]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSHSYVPMGH VWLEGDNLQN STDSRCYGPI PYGLIRGRIF FKIWPLSDFG FLRASPNGHR  60
   61 FSDD

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	4.06
Match:	1t7dA
Description:	Crystal structure of Escherichia coli type I signal peptidase in complex with a lipopeptide inhibitor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.14905070590614	bayes_pls_golite062009
transcription regulator activity	0.746023704743732	bayes_pls_golite062009
hydrolase activity	0.679628639451922	bayes_pls_golite062009
protein binding	0.595765170409461	bayes_pls_golite062009
nucleic acid binding	0.535998052361736	bayes_pls_golite062009
peptidase activity	0.19284245392981	bayes_pls_golite062009
DNA binding	0.128802761030708	bayes_pls_golite062009
catalytic activity	0.0823489300960689	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: