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View Structure Prediction Details

Protein: CALU
Organism: Homo sapiens
Length: 315 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CALU.

Description E-value Query
Range		 Subject
Range
gi|61365444, gi|... - gi|61365444|gb|AAX42709.1| calumenin [synthetic construct], gi|60653885|gb|AAX29635.1| calumenin [sy...
 2.0E-36 [1..315] [1..315]
gi|2809324 - gi|2809324|gb|AAB97725.1| calumenin [Homo sapiens]
 3.0E-36 [1..315] [1..315]
gi|76615713 - gi|76615713|ref|XP_612312.2| PREDICTED: similar to calumenin precursor isoform 1 [Bos taurus]
gi|149705852 - gi|149705852|ref|XP_001502741.1| PREDICTED: calumenin isoform 1 [Equus caballus]
 4.0E-36 [1..315] [1..315]
gi|73975637 - gi|73975637|ref|XP_849335.1| PREDICTED: similar to calumenin precursor isoform 2 [Canis familiaris]
 4.0E-36 [1..315] [1..315]
CALU_PONAB - Calumenin OS=Pongo abelii GN=CALU PE=2 SV=1
gi|55726921 - gi|55726921|emb|CAH90219.1| hypothetical protein [Pongo abelii]
 8.0E-36 [1..315] [1..315]
CALU_MESAU - Calumenin OS=Mesocricetus auratus GN=CALU PE=2 SV=1
 8.0E-36 [1..315] [1..315]
gi|37904869, gi|... - gi|37904869|gb|AAO47344.1| cardiac calumenin [Oryctolagus cuniculus], gi|130492398|ref|NP_001076203....
 1.0E-35 [1..315] [1..315]
gi|3320104, gi|1... - pir||T02784 calcium-dependent protein kinase (EC 2.7.1.-) - maize (strain W64A), gi|3320104|emb|CAA...
 2.0E-35 [2..232] [386..604]

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Predicted Domain #1
Region A:
Residues: [1-315] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLRQFLMCL SLCTAFALSK PTEKKDRVHH EPQLSDKVHN DAQSFDYDHD AFLGAEEAKT  60
   61 FDQLTPEESK ERLGKIVSKI DGDKDGFVTV DELKDWIKFA QKRWIYEDVE RQWKGHDLNE 120
  121 DGLVSWEEYK NATYGYVLDD PDPDDGFNYK QMMVRDERRF KMADKDGDLI ATKEEFTAFL 180
  181 HPEEYDYMKD IVVQETMEDI DKNADGFIDL EEYIGDMYSH DGNTDEPEWV KTEREQFVEF 240
  241 RDKNRDGKMD KEETKDWILP SDYDHAEAEA RHLVYESDQN KDGKLTKEEI VDKYDLFVGS 300
  301 QATDFGEALV RHDEF

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Detection Method: PSI-BLAST
Confidence: 5.0
Match: 1ij5A
Description: Cbp40 (plasmodial specific CaII-binding protein LAV1-2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 3.31749029935893 bayes_pls_golite062009
cytoskeletal protein binding 1.5869787076114 bayes_pls_golite062009
transcription regulator activity 1.17176381524504 bayes_pls_golite062009
protein binding 1.06263369232144 bayes_pls_golite062009
calcium ion binding 1.03474411638676 bayes_pls_golite062009
nucleic acid binding 0.849623084382492 bayes_pls_golite062009
DNA binding 0.75153529115438 bayes_pls_golite062009
ion binding 0.748522810620974 bayes_pls_golite062009
cation binding 0.747391827600734 bayes_pls_golite062009
metal ion binding 0.747391827600734 bayes_pls_golite062009
actin binding 0.637627956875516 bayes_pls_golite062009
structural molecule activity 0.535595267695359 bayes_pls_golite062009
motor activity 0.35554808768187 bayes_pls_golite062009
transcription factor binding 0.02456682442567 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle