| Protein: | POLA2 |
| Organism: | Homo sapiens |
| Length: | 598 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for POLA2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..598] | [1..598] |
|
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0.0 | [1..598] | [1..598] |
|
|
0.0 | [1..598] | [1..598] |
|
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0.0 | [1..598] | [1..600] |
|
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0.0 | [1..598] | [1..600] |
|
|
0.0 | [1..598] | [1..595] |
|
Region A: Residues: [1-114] |
1 11 21 31 41 51
| | | | | |
1 MSASAQQLAE ELQIFGLDCE EALIEKLVEL CVQYGQNEEG MVGELIAFCT STHKVGLTSE 60
61 ILNSFEHEFL SKRLSKARHS TCKDSGHAGA RDIVSIQELI EVEEEEEILL NSYT
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.751 | 0.060 | protein heterodimerization activity | a.74.1 | Cyclin-like |
| View | Download | 0.708 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.696 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.679 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.664 | N/A | N/A | a.74.1 | Cyclin-like |
|
Region A: Residues: [115-215] |
1 11 21 31 41 51
| | | | | |
1 TPSKGSQKRA ISTPETPLTK RSVSTRSPHQ LLSPSSFSPS ATPSQKYNSR SNRGEVVTSF 60
61 GLAQGVSWSG RGGAGNISLK VLGCPEALTG SYKSMFQKLP D
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.257 | 0.001 | protein heterodimerization activity | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.211 | N/A | N/A | d.54.1 | Enolase N-terminal domain-like |
|
Region A: Residues: [216-337] |
1 11 21 31 41 51
| | | | | |
1 IREVLTCKIE ELGSELKEHY KIEAFTPLLA PAQEPVTLLG QIGCDSNGKL NNKSVILEGD 60
61 REHSSGAQIP VDLSELKEYS LFPGQVVIME GINTTGRKLV ATKLYEGVPL PFYQPTEEDA 120
121 DF
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.418 | 0.960 | protein heterodimerization activity | b.1.1 | Immunoglobulin |
| View | Download | 0.303 | 0.960 | protein heterodimerization activity | b.40.4 | Nucleic acid-binding proteins |
| View | Download | 0.310 | 0.960 | protein heterodimerization activity | b.1.2 | Fibronectin type III |
| View | Download | 0.285 | 0.960 | protein heterodimerization activity | c.30.1 | PreATP-grasp domain |
| View | Download | 0.245 | 0.960 | protein heterodimerization activity | b.40.4 | Nucleic acid-binding proteins |
|
Region A: Residues: [338-598] |
1 11 21 31 41 51
| | | | | |
1 EQSMVLVACG PYTTSDSITY DPLLDLIAVI NHDRPDVCIL FGPFLDAKHE QVENCLLTSP 60
61 FEDIFKQCLR TIIEGTRSSG SHLVFVPSLR DVHHEPVYPQ PPFSYSDLSR EDKKQVQFVS 120
121 EPCSLSINGV IFGLTSTDLL FHLGAEEISS SSGTSDRFSR ILKHILTQRS YYPLYPPQED 180
181 MAIDYESFYV YAQLPVTPDV LIIPSELRYF VKDVLGCVCV NPGRLTKGQV GGTFARLYLR 240
241 RPAADGAERQ SPCIAVQVVR I
|
| Detection Method: | |
| Confidence: | 7.0 |
| Match: | 2dxlA |
| Description: | No description for 2dxlA was found. |
| Term | Confidence | Notes |
| hydrolase activity | 2.15398287574737 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 2.11518948144723 | bayes_pls_golite062009 |
| protein serine/threonine phosphatase activity | 1.72108778738758 | bayes_pls_golite062009 |
| catalytic activity | 1.39852585255405 | bayes_pls_golite062009 |
| phosphoprotein phosphatase activity | 1.23036240099336 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 0.899406797746366 | bayes_pls_golite062009 |
| binding | 0.852545739165539 | bayes_pls_golite062009 |
| phosphatase activity | 0.76188635342041 | bayes_pls_golite062009 |
| transporter activity | 0.72444760979153 | bayes_pls_golite062009 |
| protein binding | 0.682314750442084 | bayes_pls_golite062009 |
| structural molecule activity | 0.204234628453541 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.169394141800139 | bayes_pls_golite062009 |
| protein transporter activity | 0.10469955758282 | bayes_pls_golite062009 |
