| Protein: | GJA8 |
| Organism: | Homo sapiens |
| Length: | 433 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GJA8.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..433] | [1..433] |
|
|
0.0 | [1..433] | [1..432] |
|
|
0.0 | [1..433] | [1..440] |
|
|
0.0 | [1..433] | [1..435] |
|
|
0.0 | [1..433] | [1..440] |
|
|
0.0 | [1..433] | [1..439] |
|
Region A: Residues: [1-137] |
1 11 21 31 41 51
| | | | | |
1 MGDWSFLGNI LEEVNEHSTV IGRVWLTVLF IFRILILGTA AEFVWGDEQS DFVCNTQQPG 60
61 CENVCYDEAF PISHIRLWVL QIIFVSTPSL MYVGHAVHYV RMEEKRKSRE AEELGQQAGT 120
121 NGGPDQGSVK KSSGSKG
|
| Detection Method: |  |
| Confidence: | 89.823909 |
| Match: | PF00029.10 |
| Description: | No description for PF00029.10 was found. |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [138-243] |
1 11 21 31 41 51
| | | | | |
1 TKKFRLEGTL LRTYICHIIF KTLFEVGFIV GHYFLYGFRI LPLYRCSRWP CPNVVDCFVS 60
61 RPTEKTIFIL FMLSVASVSL FLNVMELGHL GLKGIRSALK RPVEQP
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [244-433] |
1 11 21 31 41 51
| | | | | |
1 LGEIPEKSLH SIAVSSIQKA KGYQLLEEEK IVSHYFPLTE VGMVETSPLP AKPFNQFEEK 60
61 ISTGPLGDLS RGYQETLPSY AQVGAQEVEG EGPPAEEGAE PEVGEKKEEA ERLTTEEQEK 120
121 VAVPEGEKVE TPGVDKEGEK EEPQSEKVSK QGLPAEKTPS LCPELTTDDA RPLSRLSKAS 180
181 SRARSDDLTV
|
| Detection Method: | |
| Confidence: | 16.30103 |
| Match: | 1r5sA |
| Description: | Connexin 43 Carboxyl Terminal Domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| gap junction channel activity | 8.7394469748353 | bayes_pls_golite062009 |
| gap junction hemi-channel activity | 6.07792310007804 | bayes_pls_golite062009 |
| channel activity | 3.3317557399613 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 3.3317557399613 | bayes_pls_golite062009 |
| transporter activity | 2.93091397928047 | bayes_pls_golite062009 |
| transmembrane transporter activity | 2.82224868778929 | bayes_pls_golite062009 |
| gated channel activity | 2.71019001063999 | bayes_pls_golite062009 |
| molecular transducer activity | 2.13986461397239 | bayes_pls_golite062009 |
| signal transducer activity | 2.13986461397239 | bayes_pls_golite062009 |
| voltage-gated channel activity | 2.0179028116167 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 1.72732246293743 | bayes_pls_golite062009 |
| PDZ domain binding | 1.67572965812401 | bayes_pls_golite062009 |
| binding | 1.64221234725269 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 1.59907041714577 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 1.48329840603397 | bayes_pls_golite062009 |
| wide pore channel activity | 1.20772405672681 | bayes_pls_golite062009 |
| receptor binding | 0.64895976014223 | bayes_pls_golite062009 |
| protein binding | 0.634982583867058 | bayes_pls_golite062009 |
| protein domain specific binding | 0.49888190331002 | bayes_pls_golite062009 |
| SH3 domain binding | 0.0507592042406799 | bayes_pls_golite062009 |
