YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: DUS2L
Organism: Homo sapiens
Length: 493 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DUS2L.

Description E-value Query
Range
Subject
Range
DUS2L_MOUSE - tRNA-dihydrouridine(20) synthase [NAD(P)+]-like OS=Mus musculus GN=Dus2 PE=1 SV=1
0.0 [1..492] [1..492]
gi|114663242, gi... - gi|114663252|ref|XP_001166928.1| PREDICTED: dihydrouridine synthase 2-like, SMM1 homolog isoform 9 [...
0.0 [1..493] [1..493]
gi|157818491, gi... - gi|62665191|ref|XP_214665.3| PREDICTED: similar to tRNA-dihydrouridine synthase 2-like [Rattus norve...
0.0 [1..492] [1..492]
gi|111308646, gi... - gi|76640144|ref|XP_586835.2| PREDICTED: similar to tRNA-dihydrouridine synthase 2-like isoform 1 [Bo...
0.0 [1..493] [1..493]
gi|109128993 - gi|109128993|ref|XP_001097732.1| PREDICTED: dihydrouridine synthase 2-like (SMM1, S. cerevisiae) [Ma...
3.0E-98 [1..493] [1..492]
gi|73957464 - gi|73957464|ref|XP_546866.2| PREDICTED: similar to dihydrouridine synthase 2-like (SMM1, S. cerevisi...
7.0E-96 [7..493] [74..560]
gi|50753664 - gi|50753664|ref|XP_414079.1| PREDICTED: similar to hypothetical protein FLJ20399 [Gallus gallus]
5.0E-75 [7..473] [6..471]
CG1434-PA, FBpp0... - This gene is referred to in FlyBase by the symbol Dmel\CG1434 (CG1434, FBgn0030554). It is a protein...
1.0E-68 [8..448] [20..471]

Back

Predicted Domain #1
Region A:
Residues: [1-346]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MILNSLSLCY HNKLILAPMV RVGTLPMRLL ALDYGADIVY CEELIDLKMI QCKRVVNEVL  60
   61 STVDFVAPDD RVVFRTCERE QNRVVFQMGT SDAERALAVA RLVENDVAGI DVNMGCPKQY 120
  121 STKGGMGAAL LSDPDKIEKI LSTLVKGTRR PVTCKIRILP SLEDTLSLVK RIERTGIAAI 180
  181 AVHGRKREER PQHPVSCEVI KAIADTLSIP VIANGGSHDH IQQYSDIEDF RQATAASSVM 240
  241 VARAAMWNPS IFLKEGLRPL EEVMQKYIRY AVQYDNHYTN TKYCLCQMLR EQLESPQGRL 300
  301 LHAAQSSREI CEAFGLGAFY EETTQELDAQ QARLSAKTSE QTGEPA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.221849
Match: 1vhnA
Description: Crystal structure of a putative flavin oxidoreductase with flavin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.94749091175302 bayes_pls_golite062009
tRNA dihydrouridine synthase activity 1.94490879164338 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [347-493]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDTSGVIKMA VKFDRRAYPA QITPKMCLLE WCRREKLAQP VYETVQRPLD RLFSSIVTVA  60
   61 EQKYQSTLWD KSKKLAEQAA AIVCLRSQGL PEGRLGEESP SLHKRKREAP DQDPGGPRAQ 120
  121 ELAQPGDLCK KPFVALGSGE ESPLEGW

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.09691
Match: 1whnA
Description: Solution structure of the dsRBD from hypothetical protein BAB26260
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 2.539601915417 bayes_pls_golite062009
binding 1.80132856651319 bayes_pls_golite062009
nucleic acid binding 1.57684875880134 bayes_pls_golite062009
double-stranded RNA binding 1.06206547102508 bayes_pls_golite062009
protein binding 0.927977287431555 bayes_pls_golite062009
DNA binding 0.0536460773631342 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle