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Protein Overview: CG1434-PA, FBpp0...

General Information:
Name(s) found: FBpp0308524 [FlyBase]
CG1434-PA / FBpp0073720 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • type=protein; loc=X:join(14132407..14132614,14132676..14133638,14133706..14133956); ID=FBpp0308524; name=CG1434-PB; parent=FBgn0030554,FBtr0339437; dbxref=FlyBase:FBpp0308524,FlyBase_Annotation_IDs:CG1434-PB; MD5=8a3bc6f4eeff0a989775a745d0d1f9bd; length=473; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG1434 (CG1434, FBgn0030554). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:14132022..14134188. It has the cytological map location 12E5. Based on sequence similarity, it is predicted to have molecular function</span>: tRNA dihydrouridine synthase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction; tRNA processing. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 473 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: tRNA processing [IEA]
    oxidation reduction [IEA]
    Molecular Function: tRNA dihydrouridine synthase activity [ISS]
    FAD binding [IEA]
    double-stranded RNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRLPTILRK SFSMKTRQRL DYRNKLILAP MVRVGTLPMR LLALEMGADI VYTEELVDIK  60
   61 LIKSIRRPNP ALGTVDFVDP SDGTIVFRTC AQETSRLVLQ MGTSDAGRAL AVGKLLQRDI 120
  121 SGLDINMGCP KEFSIKGGMG AALLADPDKA AHILRTLCSG LDIPVTCKIR ILPDVEGTID 180
  181 LVQKLAATGI AAIGIHARTR DERPQHPAHP EVLRAVAQAV DIPIIANGGS KNMHCYDDLR 240
  241 KFQMECGADS VMVARAAQIN VSIFRPEGLL PMDELIEKYL RLCVDYDNAP HNAKYCVQSI 300
  301 LRELQETPRG KRFLQCQTLQ QICEIWELGD YCRRKQRELK TMGNSGRAEV EPPEALAKRQ 360
  361 KLEDAAIAIT DEYDGIICRH MPFLRSTYPS DNHLPKTQLY VHAVKTGKSP PAYETQQCDK 420
  421 LFRSICTYDG QRFSSSFWEK NKKQAEQGAA LVALLHLGQL EAEVLRDNGS LLN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..342] PSI-BLAST 53.09691 Crystal structure of a putative flavin oxidoreductase with flavin
    2 View Details [343..473] PSI-BLAST 23.045757 Solution structure of the dsRBD from hypothetical protein BAB26260

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.94749091175302 bayes_pls_golite062009
  • tRNA dihydrouridine synthase activity
    		•  1.94490879164338 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.03692680161964 bayes_pls_golite062009
  • binding
    		•  0.68572942532795 bayes_pls_golite062009
    2
    Term Confidence Notes
  • RNA binding
    		•  3.49736268261512 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.95361490759242 bayes_pls_golite062009
  • binding
    		•  2.70269289824982 bayes_pls_golite062009
  • DNA binding
    		•  1.51133867432475 bayes_pls_golite062009
  • double-stranded RNA binding
    		•  1.46317494664076 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.25950932467779 bayes_pls_golite062009
  • protein binding
    		•  1.18355143131643 bayes_pls_golite062009
  • double-stranded RNA adenosine deaminase activity
    		•  0.642670918049453 bayes_pls_golite062009
  • transcription factor activity
    		•  0.42419387757895 bayes_pls_golite062009
  • protein kinase activity
    		•  0.174129357494585 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.73

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle