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Protein Overview: DUS2L

General Information:
Name(s) found: DUS2L [HGNC (HUGO)]
Description(s) found:
Found 40 descriptions.
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  • dihydrouridine synthase 2-like, SMM1 homolog (S. cerevisiae) [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 493 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MILNSLSLCY HNKLILAPMV RVGTLPMRLL ALDYGADIVY CEELIDLKMI QCKRVVNEVL  60
   61 STVDFVAPDD RVVFRTCERE QNRVVFQMGT SDAERALAVA RLVENDVAGI DVNMGCPKQY 120
  121 STKGGMGAAL LSDPDKIEKI LSTLVKGTRR PVTCKIRILP SLEDTLSLVK RIERTGIAAI 180
  181 AVHGRKREER PQHPVSCEVI KAIADTLSIP VIANGGSHDH IQQYSDIEDF RQATAASSVM 240
  241 VARAAMWNPS IFLKEGLRPL EEVMQKYIRY AVQYDNHYTN TKYCLCQMLR EQLESPQGRL 300
  301 LHAAQSSREI CEAFGLGAFY EETTQELDAQ QARLSAKTSE QTGEPAEDTS GVIKMAVKFD 360
  361 RRAYPAQITP KMCLLEWCRR EKLAQPVYET VQRPLDRLFS SIVTVAEQKY QSTLWDKSKK 420
  421 LAEQAAAIVC LRSQGLPEGR LGEESPSLHK RKREAPDQDP GGPRAQELAQ PGDLCKKPFV 480
  481 ALGSGEESPL EGW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..346] PSI-BLAST 40.221849 Crystal structure of a putative flavin oxidoreductase with flavin
    2 View Details [347..493] PSI-BLAST 27.09691 Solution structure of the dsRBD from hypothetical protein BAB26260

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.94749091175302 bayes_pls_golite062009
  • tRNA dihydrouridine synthase activity
    		•  1.94490879164338 bayes_pls_golite062009
    2
    Term Confidence Notes
  • RNA binding
    		•  2.539601915417 bayes_pls_golite062009
  • binding
    		•  1.80132856651319 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.57684875880134 bayes_pls_golite062009
  • double-stranded RNA binding
    		•  1.06206547102508 bayes_pls_golite062009
  • protein binding
    		•  0.927977287431555 bayes_pls_golite062009
  • DNA binding
    		•  0.0536460773631342 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle