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View Structure Prediction Details

Protein: EPC1
Organism: Homo sapiens
Length: 836 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EPC1.

Description E-value Query
Range
Subject
Range
gi|73948773 - gi|73948773|ref|XP_535156.2| PREDICTED: similar to enhancer of polycomb 1 isoform 1 [Canis familiari...
0.0 [1..836] [1..842]
gi|114629985 - gi|114629985|ref|XP_507733.2| PREDICTED: enhancer of polycomb 1 isoform 4 [Pan troglodytes]
0.0 [1..836] [1..842]
gi|109505898, gi... - gi|62663676|ref|XP_225457.3| PREDICTED: similar to enhancer of polycomb homolog 1 isoform 2 [Rattus ...
0.0 [1..836] [1..835]
gi|119606378, gi... - gi|55665075|emb|CAH70453.1| enhancer of polycomb homolog 1 (Drosophila) [Homo sapiens], gi|55662157|...
0.0 [1..836] [1..813]
EPC1_MOUSE - Enhancer of polycomb homolog 1 OS=Mus musculus GN=Epc1 PE=1 SV=1
0.0 [1..836] [1..813]

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Predicted Domain #1
Region A:
Residues: [1-65]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKLSFRARA LDASKPLPVF RCEDLPDLHE YASINRAVPQ MPTGMEKEEE SEHHLQRAIS  60
   61 AQQVY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [66-278]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEKRDNMVIP VPEAESNIAY YESIYPGEFK MPKQLIHIQP FSLDAEQPDY DLDSEDEVFV  60
   61 NKLKKKMDIC PLQFEEMIDR LEKGSGQQPV SLQEAKLLLK EDDELIREVY EYWIKKRKNC 120
  121 RGPSLIPSVK QEKRDGSSTN DPYVAFRRRT EKMQTRKNRK NDEASYEKML KLRRDLSRAV 180
  181 TILEMIKRRE KSKRELLHLT LEIMEKRYNL GDY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [279-390]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGEIMSEVMA QRQPMKPTYA IPIIPITNSS QFKHQEAMDV KEFKVNKQDK ADLIRPKRKY  60
   61 EKKPKVLPSS AAATPQQTSP AALPVFNAKD LNQYDFPSSD EEPLSQVLSG SS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.39794
Match: 2d9eA
Description: No description for 2d9eA was found.

Predicted Domain #4
Region A:
Residues: [391-533]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EAEEDNDPDG PFAFRRKAGC QYYAPHLDQT GNWPWTSPKD GGLGDVRYRY CLTTLTVPQR  60
   61 CIGFARRRVG RGGRVLLDRA HSDYDSVFHH LDLEMLSSPQ HSPVNQFANT SETNTSDKSF 120
  121 SKDLSQILVN IKSCRWRHFR PRT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.579 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.540 d.110.3 PYP-like sensor domain (PAS domain)
View Download 0.479 d.79.3 L30e-like
View Download 0.468 d.110.3 PYP-like sensor domain (PAS domain)
View Download 0.447 c.2.1 NAD(P)-binding Rossmann-fold domains

Predicted Domain #5
Region A:
Residues: [534-676]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSLHDSDNDE LSCRKLYRSI NRTGTAQPGT QTCSTSTQSK SSSGSAHFAF TAEQYQQHQQ  60
   61 QLALMQKQQL AQIQQQQANS NSSTNTSQNL ASNQQKSGFR LNIQGLERTL QGFVSKTLDS 120
  121 ASAQFAASAL VTSEQLMGFK MKD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [677-836]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVVLGIGVNG VLPASGVYKG LHLSSTTPTA LVHTSPSTAG SALLQPSNIT QTSSSHSALS  60
   61 HQVTAANSAT TQVLIGNNIR LTVPSSVATV NSIAPINARH IPRTLSAVPS SALKLAAAAN 120
  121 CQVSKVPSSS SVDSVPRENH ESEKPALNNI ADNTVAMEVT 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle