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View Structure Prediction Details

Protein: EPC1
Organism: Homo sapiens
Length: 836 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EPC1.

Description E-value Query
Range
Subject
Range
gi|73948773 - gi|73948773|ref|XP_535156.2| PREDICTED: similar to enhancer of polycomb 1 isoform 1 [Canis familiari...
0.0 [1..836] [1..842]
gi|114629985 - gi|114629985|ref|XP_507733.2| PREDICTED: enhancer of polycomb 1 isoform 4 [Pan troglodytes]
0.0 [1..836] [1..842]
gi|109505898, gi... - gi|62663676|ref|XP_225457.3| PREDICTED: similar to enhancer of polycomb homolog 1 isoform 2 [Rattus ...
0.0 [1..836] [1..835]
gi|119606378, gi... - gi|55665075|emb|CAH70453.1| enhancer of polycomb homolog 1 (Drosophila) [Homo sapiens], gi|55662157|...
0.0 [1..836] [1..813]
EPC1_MOUSE - Enhancer of polycomb homolog 1 OS=Mus musculus GN=Epc1 PE=1 SV=1
0.0 [1..836] [1..813]

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Predicted Domain #1
Region A:
Residues: [1-65]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKLSFRARA LDASKPLPVF RCEDLPDLHE YASINRAVPQ MPTGMEKEEE SEHHLQRAIS  60
   61 AQQVY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [66-278]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEKRDNMVIP VPEAESNIAY YESIYPGEFK MPKQLIHIQP FSLDAEQPDY DLDSEDEVFV  60
   61 NKLKKKMDIC PLQFEEMIDR LEKGSGQQPV SLQEAKLLLK EDDELIREVY EYWIKKRKNC 120
  121 RGPSLIPSVK QEKRDGSSTN DPYVAFRRRT EKMQTRKNRK NDEASYEKML KLRRDLSRAV 180
  181 TILEMIKRRE KSKRELLHLT LEIMEKRYNL GDY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [279-390]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGEIMSEVMA QRQPMKPTYA IPIIPITNSS QFKHQEAMDV KEFKVNKQDK ADLIRPKRKY  60
   61 EKKPKVLPSS AAATPQQTSP AALPVFNAKD LNQYDFPSSD EEPLSQVLSG SS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.39794
Match: 2d9eA
Description: No description for 2d9eA was found.

Predicted Domain #4
Region A:
Residues: [391-533]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EAEEDNDPDG PFAFRRKAGC QYYAPHLDQT GNWPWTSPKD GGLGDVRYRY CLTTLTVPQR  60
   61 CIGFARRRVG RGGRVLLDRA HSDYDSVFHH LDLEMLSSPQ HSPVNQFANT SETNTSDKSF 120
  121 SKDLSQILVN IKSCRWRHFR PRT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [534-676]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSLHDSDNDE LSCRKLYRSI NRTGTAQPGT QTCSTSTQSK SSSGSAHFAF TAEQYQQHQQ  60
   61 QLALMQKQQL AQIQQQQANS NSSTNTSQNL ASNQQKSGFR LNIQGLERTL QGFVSKTLDS 120
  121 ASAQFAASAL VTSEQLMGFK MKD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [677-836]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVVLGIGVNG VLPASGVYKG LHLSSTTPTA LVHTSPSTAG SALLQPSNIT QTSSSHSALS  60
   61 HQVTAANSAT TQVLIGNNIR LTVPSSVATV NSIAPINARH IPRTLSAVPS SALKLAAAAN 120
  121 CQVSKVPSSS SVDSVPRENH ESEKPALNNI ADNTVAMEVT 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle