| Protein: | AKR1C1 |
| Organism: | Homo sapiens |
| Length: | 323 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AKR1C1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..323] | [1..323] |
|
|
0.0 | [1..323] | [1..323] |
|
|
0.0 | [1..323] | [1..323] |
|
|
0.0 | [1..323] | [1..323] |
|
|
0.0 | [1..323] | [1..323] |
|
Region A: Residues: [1-323] |
1 11 21 31 41 51
| | | | | |
1 MDSKYQCVKL NDGHFMPVLG FGTYAPAEVP KSKALEATKL AIEAGFRHID SAHLYNNEEQ 60
61 VGLAIRSKIA DGSVKREDIF YTSKLWCNSH RPELVRPALE RSLKNLQLDY VDLYLIHFPV 120
121 SVKPGEEVIP KDENGKILFD TVDLCATWEA VEKCKDAGLA KSIGVSNFNR RQLEMILNKP 180
181 GLKYKPVCNQ VECHPYFNQR KLLDFCKSKD IVLVAYSALG SHREEPWVDP NSPVLLEDPV 240
241 LCALAKKHKR TPALIALRYQ LQRGVVVLAK SYNEQRIRQN VQVFEFQLTS EEMKAIDGLN 300
301 RNVRYLTLDI FAGPPNYPFS DEY
|
| Detection Method: |  |
| Confidence: | 108.0 |
| Match: | 1ihiA |
| Description: | 3-alpha-hydroxysteroid dehydrogenase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| aldehyde reductase activity | 5.07106269693426 | bayes_pls_golite062009 |
| L-glucuronate reductase activity | 4.06568552614053 | bayes_pls_golite062009 |
| arabinose reductase activity | 3.28910924444005 | bayes_pls_golite062009 |
| xylose reductase activity | 3.28910924444005 | bayes_pls_golite062009 |
| glucose 1-dehydrogenase (NADP+) activity | 2.68048267823456 | bayes_pls_golite062009 |
| aldo-keto reductase activity | 2.57303336304449 | bayes_pls_golite062009 |
| trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity | 2.43245618396666 | bayes_pls_golite062009 |
| 3-alpha-hydroxysteroid dehydrogenase (B-specific) activity | 2.43245618396666 | bayes_pls_golite062009 |
| alpha-keto ester reductase activity | 2.31616201247794 | bayes_pls_golite062009 |
| alpha-keto amide reductase activity | 2.31616201247794 | bayes_pls_golite062009 |
| steroid dehydrogenase activity | 2.19555484888528 | bayes_pls_golite062009 |
| steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 1.87468990921314 | bayes_pls_golite062009 |
| catalytic activity | 1.68179794468736 | bayes_pls_golite062009 |
| glucose 1-dehydrogenase activity | 1.55697325009049 | bayes_pls_golite062009 |
| bile acid transmembrane transporter activity | 1.47447940903315 | bayes_pls_golite062009 |
| monocarboxylic acid transmembrane transporter activity | 1.45034485133104 | bayes_pls_golite062009 |
| binding | 1.3044513338497 | bayes_pls_golite062009 |
| bile acid binding | 1.28757511368757 | bayes_pls_golite062009 |
| transporter activity | 1.24767072239634 | bayes_pls_golite062009 |
| oxidoreductase activity | 1.22645031212774 | bayes_pls_golite062009 |
| organic acid transmembrane transporter activity | 1.20678148401125 | bayes_pls_golite062009 |
| carboxylic acid transmembrane transporter activity | 1.19919645230426 | bayes_pls_golite062009 |
| steroid dehydrogenase activity, acting on the CH-CH group of donors | 1.15597377782029 | bayes_pls_golite062009 |
| 3-oxo-5-beta-steroid 4-dehydrogenase activity | 1.15597377782029 | bayes_pls_golite062009 |
| protein binding | 1.06359558718341 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.03420335553507 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on CH-OH group of donors | 0.868027162240181 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 0.86591084281532 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.783004917746429 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.544360068128604 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.260605752589411 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 0.0547047948210824 | bayes_pls_golite062009 |
