| Protein: | DNAJC3 |
| Organism: | Homo sapiens |
| Length: | 504 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DNAJC3.
| Description | E-value | Query Range |
Subject Range |
|
|
4.0E-58 | [35..487] | [290..739] |
|
|
7.0E-58 | [1..504] | [1..504] |
|
|
1.0E-57 | [1..504] | [1..504] |
|
|
4.0E-57 | [1..504] | [1..504] |
|
|
1.0E-56 | [1..504] | [1..504] |
|
|
3.0E-56 | [5..381] | [290..638] |
|
|
3.0E-56 | [1..504] | [1..504] |
|
|
8.0E-56 | [1..504] | [1..504] |
|
Region A: Residues: [1-401] |
1 11 21 31 41 51
| | | | | |
1 MVAPGSVTSR LGSVFPFLLV LVDLQYEGAE CGVNADVEKH LELGKKLLAA GQLADALSQF 60
61 HAAVDGDPDN YIAYYRRATV FLAMGKSKAA LPDLTKVIQL KMDFTAARLQ RGHLLLKQGK 120
121 LDEAEDDFKK VLKSNPSENE EKEAQSQLIK SDEMQRLRSQ ALNAFGSGDY TAAIAFLDKI 180
181 LEVCVWDAEL RELRAECFIK EGEPRKAISD LKAASKLKND NTEAFYKIST LYYQLGDHEL 240
241 SLSEVRECLK LDQDHKRCFA HYKQVKKLNK LIESAEELIR DGRYTDATSK YESVMKTEPS 300
301 IAEYTVRSKE RICHCFSKDE KPVEAIRVCS EVLQMEPDNV NALKDRAEAY LIEEMYDEAI 360
361 QDYETAQEHN ENDQQIREGL EKAQRLLKQS QKRDYYKILG V
|
| Detection Method: |  |
| Confidence: | 41.69897 |
| Match: | 1w3bA |
| Description: | The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha. |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.07985546140154 | bayes_pls_golite062009 |
| protein binding | 1.6279032205159 | bayes_pls_golite062009 |
| heat shock protein binding | 1.23450221149054 | bayes_pls_golite062009 |
| unfolded protein binding | 1.03065657981002 | bayes_pls_golite062009 |
| enzyme binding | 0.44905827271946 | bayes_pls_golite062009 |
| transcription regulator activity | 0.389874293041007 | bayes_pls_golite062009 |
| nucleic acid binding | 0.35164886746762 | bayes_pls_golite062009 |
| DNA binding | 0.244553192560639 | bayes_pls_golite062009 |
|
Region A: Residues: [402-504] |
1 11 21 31 41 51
| | | | | |
1 KRNAKKQEII KAYRKLALQW HPDNFQNEEE KKKAEKKFID IAAAKEVLSD PEMRKKFDDG 60
61 EDPLDAESQQ GGGGNPFHRS WNSWQGFNPF SSGGPFRFKF HFN
|
| Detection Method: | |
| Confidence: | 8.045757 |
| Match: | 1xblA |
| Description: | NMR STRUCTURE OF THE J-DOMAIN (RESIDUES 2-76) IN THE ESCHERICHIA COLI N-TERMINAL FRAGMENT (RESIDUES 2-108) OF THE MOLECULAR CHAPERONE DNAJ, 20 STRUCTURES |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| unfolded protein binding | 3.04403163860617 | bayes_pls_golite062009 |
| heat shock protein binding | 2.06176335248157 | bayes_pls_golite062009 |
| binding | 1.99149924818543 | bayes_pls_golite062009 |
| protein binding | 1.60937254813642 | bayes_pls_golite062009 |
| chaperone binding | 1.57325829043476 | bayes_pls_golite062009 |
| Hsp70 protein binding | 0.541755903922701 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.472629059184113 | bayes_pls_golite062009 |
| kinase activity | 0.466886050736282 | bayes_pls_golite062009 |
| protein kinase activity | 0.36885370400914 | bayes_pls_golite062009 |
| nucleic acid binding | 0.358068043290742 | bayes_pls_golite062009 |
| transcription regulator activity | 0.341554040400357 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.32785918835419 | bayes_pls_golite062009 |
| DNA binding | 0.170257507064939 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.132809854474755 | bayes_pls_golite062009 |
| catalytic activity | 0.106988907594358 | bayes_pls_golite062009 |
