YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: GNPDA1
Organism: Homo sapiens
Length: 289 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GNPDA1.

Description E-value Query
Range		 Subject
Range
gi|148226212, gi... - gi|38014417|gb|AAH60459.1| MGC68566 protein [Xenopus laevis], gi|148226212|ref|NP_001083469.1| hypot...
 0.0 [1..289] [1..289]
gi|40789072 - gi|40789072|dbj|BAA06544.2| KIAA0060 [Homo sapiens]
 0.0 [1..289] [29..317]
GNPI1_MOUSE, GNP... - Glucosamine-6-phosphate isomerase - Mus musculus (Mouse), Glucosamine-6-phosphate isomerase 1 OS=Mus...
 0.0 [1..289] [1..289]
gi|114602426 - gi|114602426|ref|XP_001139968.1| PREDICTED: similar to KIAA0060 [Pan troglodytes]
 0.0 [1..289] [73..361]
ENSOCUP000000145... - pep:novel chromosome:oryCun2:3:24036089:24042485:-1 gene:ENSOCUG00000016963 transcript:ENSOCUT000000...
GNPI1_BOVIN - Glucosamine-6-phosphate isomerase 1 OS=Bos taurus GN=GNPDA1 PE=2 SV=1
 0.0 [1..289] [1..289]
GNPI1_PONAB - Glucosamine-6-phosphate isomerase 1 OS=Pongo abelii GN=GNPDA1 PE=2 SV=1
GNPI_PONPY - Glucosamine-6-phosphate isomerase - Pongo pygmaeus (Orangutan)
 0.0 [1..289] [1..289]
gi|197246475, gi... - gi|201861364|ref|NP_001128467.1| glucosamine-6-phosphate deaminase 1 [Rattus norvegicus], gi|1972464...
 0.0 [1..289] [1..289]
GNPI1_MESAU - Glucosamine-6-phosphate isomerase 1 OS=Mesocricetus auratus GN=GNPDA1 PE=2 SV=1
 0.0 [1..289] [1..289]

Back

Predicted Domain #1
Region A:
Residues: [1-289] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLIILEHYS QASEWAAKYI RNRIIQFNPG PEKYFTLGLP TGSTPLGCYK KLIEYYKNGD  60
   61 LSFKYVKTFN MDEYVGLPRD HPESYHSFMW NNFFKHIDIH PENTHILDGN AVDLQAECDA 120
  121 FEEKIKAAGG IELFVGGIGP DGHIAFNEPG SSLVSRTRVK TLAMDTILAN ARFFDGELTK 180
  181 VPTMALTVGV GTVMDAREVM ILITGAHKAF ALYKAIEEGV NHMWTVSAFQ QHPRTVFVCD 240
  241 EDATLELKVK TVKYFKGLML VHNKLVDPLY SIKEKETEKS QSSKKPYSD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 114.0
Match: 1ne7A
Description: HUMAN GLUCOSAMINE-6-PHOSPHATE DEAMINASE ISOMERASE AT 1.75 A RESOLUTION COMPLEXED WITH N-ACETYL-GLUCOSAMINE-6-PHOSPHATE AND 2-DEOXY-2-AMINO-GLUCITOL-6-PHOSPHATE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glucosamine-6-phosphate deaminase activity 4.20201419087614 bayes_pls_golite062009
intramolecular oxidoreductase activity 2.15381323621148 bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses 1.65800801564277 bayes_pls_golite062009
catalytic activity 1.31732715713197 bayes_pls_golite062009
ribose-5-phosphate isomerase activity 1.21538742769205 bayes_pls_golite062009
nucleic acid binding 1.15193795385115 bayes_pls_golite062009
binding 0.790197816513984 bayes_pls_golite062009
transcription regulator activity 0.527142798518238 bayes_pls_golite062009
6-phosphogluconolactonase activity 0.480819049634739 bayes_pls_golite062009
DNA binding 0.465566131334457 bayes_pls_golite062009
isomerase activity 0.102415560220489 bayes_pls_golite062009
protein binding 0.0458232930850621 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle