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View Structure Prediction Details

Protein: NSMCE2
Organism: Homo sapiens
Length: 247 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NSMCE2.

Description E-value Query
Range		 Subject
Range
NSE2_RAT - E3 SUMO-protein ligase NSE2 OS=Rattus norvegicus GN=Nsmce2 PE=2 SV=1
 1.0E-50 [1..247] [1..247]
gi|16552560 - gi|16552560|dbj|BAB71338.1| unnamed protein product [Homo sapiens]
 2.0E-46 [1..247] [1..247]
gi|21312038, gi|... - gi|21312038|ref|NP_081022.1| non-SMC element 2, MMS21 homolog [Mus musculus], gi|12834505|dbj|BAB229...
 2.0E-43 [1..247] [1..247]
NSE2_BOVIN - E3 SUMO-protein ligase NSE2 OS=Bos taurus GN=NSMCE2 PE=2 SV=1
 7.0E-40 [15..245] [17..247]
NSE2_XENLA - E3 SUMO-protein ligase NSE2 OS=Xenopus laevis GN=nsmce2 PE=2 SV=1
 6.0E-37 [11..245] [5..238]
PUB13_ARATH - U-box domain-containing protein 13 OS=Arabidopsis thaliana GN=PUB13 PE=1 SV=1
 4.0E-33 [11..242] [99..326]
SL11_ORYSI - Protein spotted leaf 11 OS=Oryza sativa subsp. indica GN=SPL11 PE=1 SV=2
SPL11_ORYSA - Spotted leaf protein 11 (Spotted leaf11) (Cell death-related protein SPL11) - Oryza sativa (Rice)
SL11_ORYSJ - E3 ubiquitin-protein ligase SPL11 OS=Oryza sativa subsp. japonica GN=SPL11 PE=1 SV=2
 5.0E-30 [18..242] [128..343]
gi|77556856 - gi|77556856|gb|ABA99652.1| Spotted leaf protein 11, putative, expressed [Oryza sativa (japonica cult...
 5.0E-30 [18..242] [9..224]

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Predicted Domain #1
Region A:
Residues: [1-155] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPGRSSSNSG STGFISFSGV ESALSSLKNF QACINSGMDT ASSVALDLVE SQTEVSSEYS  60
   61 MDKAMVEFAT LDRQLNHYVK AVQSTINHVK EERPEKIPDL KLLVEKKFLA LQSKNSDADF 120
  121 QNNEKFVQFK QQLKELKKQC GLQADREADG TEGVD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score		 GO
Score		 GO
Term		 SCOP
Match		 SCOP Description
View Download 0.419 N/A N/A a.118.9 ENTH/VHS domain
View Download 0.382 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.363 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.363 N/A N/A f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.342 N/A N/A a.1.1 Globin-like

Predicted Domain #2
Region A:
Residues: [156-247] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDIIVTQSQT NFTCPITKEE MKKPVKNKVC GHTYEEDAIV RMIESRQKRK KKAYCPQIGC  60
   61 SHTDIRKSDL IQDEALRRAI ENHNKKRHRH SE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.39794
Match: 2yu4A
Description: No description for 2yu4A was found.
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle