YRC Public Data Repository - Protein Structure Prediction

Protein:	RPS10
Organism:	Homo sapiens
Length:	165 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPS10.

Description	E-value	Query Range	Subject Range
gi\|114606978 - gi\|114606978\|ref\|XP_001171658.1\| PREDICTED: similar to ribosomal protein S10 isoform 3 [Pan troglody... tr\|A0A1W2PQS6\|A0... - IPI:IPI00978180.1\|REFSEQ:NP_001189399 Tax_Id=9606 Gene_Symbol=RPS10-NUDT3 RPS10-NUDT3 protein, Tax_I...	5.0E-82	[1..152]	[1..152]
gi\|109096350 - gi\|109096350\|ref\|XP_001093979.1\| PREDICTED: similar to 40S ribosomal protein S10 [Macaca mulatta]	4.0E-81	[1..165]	[1..165]
gi\|55665989 - gi\|55665989\|emb\|CAH73101.1\| ribosomal protein S10 [Homo sapiens]	3.0E-80	[1..152]	[1..152]
gi\|73972594 - gi\|73972594\|ref\|XP_532112.2\| PREDICTED: similar to 40S ribosomal protein S10 [Canis familiaris]	3.0E-79	[1..152]	[150..301]
gi\|62662495, gi\|... - gi\|62662495\|ref\|XP_224779.2\| PREDICTED: similar to ribosomal protein S10 [Rattus norvegicus], gi\|109...	2.0E-76	[1..165]	[1..163]
gi\|94401105, gi\|... - gi\|94401105\|ref\|XP_992604.1\| PREDICTED: similar to ribosomal protein S10 [Mus musculus], gi\|94400441...	3.0E-76	[1..165]	[1..165]

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Predicted Domain #1

Region A:
Residues: [1-165]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLMPKKNRIA IYELLFKEGV MVAKKDVHMP KHPELADKNV PNLHVMKAMQ SLKSRGYVKE  60
   61 QFAWRHFYWY LTNEGIQYLR DYLHLPPEIV PATLRRSRPE TGRPRPKGLE GERPARLTRG 120
  121 EADRDTYRRS AVPPGADKKA EAGAGSATEF QFRGGFGRGR GQPPQ

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	0.963
Match:	1ub9A
Description:	Structure of the transcriptional regulator homologue protein from Pyrococcus horikoshii OT3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
structural constituent of ribosome	5.31568733625259	bayes_pls_golite062009
structural molecule activity	5.08906334129014	bayes_pls_golite062009
transcription regulator activity	3.15604421023994	bayes_pls_golite062009
nucleic acid binding	3.03746013592931	bayes_pls_golite062009
DNA binding	2.94000725003786	bayes_pls_golite062009
binding	2.7993872466812	bayes_pls_golite062009
transcription factor activity	2.26980753972323	bayes_pls_golite062009
sequence-specific DNA binding	0.948991080726164	bayes_pls_golite062009
transcription activator activity	0.818477312720578	bayes_pls_golite062009
protein binding	0.749376520208656	bayes_pls_golite062009
transcription repressor activity	0.679859821399589	bayes_pls_golite062009
RNA binding	0.352569950847387	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.205052011867554	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: