| Protein: | PRKCE |
| Organism: | Homo sapiens |
| Length: | 737 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRKCE.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..737] | [1..737] |
|
|
0.0 | [1..737] | [1..737] |
|
|
0.0 | [1..737] | [1..737] |
|
|
0.0 | [1..737] | [1..736] |
|
|
0.0 | [1..737] | [1..736] |
|
|
0.0 | [1..734] | [1..739] |
|
Region A: Residues: [1-135] |
1 11 21 31 41 51
| | | | | |
1 MVVFNGLLKI KICEAVSLKP TAWSLRHAVG PRPQTFLLDP YIALNVDDSR IGQTATKQKT 60
61 NSPAWHDEFV TDVCNGRKIE LAVFHDAPIG YDDFVANCTI QFEELLQNGS RHFEDWIDLE 120
121 PEGRVYVIID LSGSS
|
| Detection Method: |  |
| Confidence: | 12.30103 |
| Match: | 1gmiA |
| Description: | Domain from protein kinase C epsilon |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| calcium-dependent phospholipid binding | 4.44639260287301 | bayes_pls_golite062009 |
| binding | 2.77482286467294 | bayes_pls_golite062009 |
| phospholipid binding | 2.74013385479058 | bayes_pls_golite062009 |
| protein binding | 2.38962673708753 | bayes_pls_golite062009 |
| neurexin binding | 1.99616093461872 | bayes_pls_golite062009 |
| receptor activity | 1.8680110497448 | bayes_pls_golite062009 |
| molecular transducer activity | 1.5224906678897 | bayes_pls_golite062009 |
| signal transducer activity | 1.5224906678897 | bayes_pls_golite062009 |
| lipid binding | 1.47484095830847 | bayes_pls_golite062009 |
| profilin binding | 1.32619249806841 | bayes_pls_golite062009 |
| transporter activity | 1.2628067945512 | bayes_pls_golite062009 |
| cation binding | 0.860272194694588 | bayes_pls_golite062009 |
| metal ion binding | 0.860272194694588 | bayes_pls_golite062009 |
| ion binding | 0.853522493520737 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.816751946072324 | bayes_pls_golite062009 |
| calmodulin binding | 0.66928366000251 | bayes_pls_golite062009 |
| syntaxin-1 binding | 0.655976398483981 | bayes_pls_golite062009 |
| hydrolase activity | 0.501946993060588 | bayes_pls_golite062009 |
| SNARE binding | 0.3731056408292 | bayes_pls_golite062009 |
|
Region A: Residues: [136-265] |
1 11 21 31 41 51
| | | | | |
1 GEAPKDNEER VFRERMRPRK RQGAVRRRVH QVNGHKFMAT YLRQPTYCSH CRDFIWGVIG 60
61 KQGYQCQVCT CVVHKRCHEL IITKCAGLKK QETPDQVGSQ RFSVNMPHKF GIHNYKVPTF 120
121 CDHCGSLLWG
|
| Detection Method: | |
| Confidence: | 3.22 |
| Match: | 1r79A |
| Description: | Solution Structure of The C1 Domain of The Human Diacylglycerol Kinase Delta |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 2.82097223032126 | bayes_pls_golite062009 |
| binding | 2.71288992341677 | bayes_pls_golite062009 |
| protein binding | 2.2604757016607 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 2.18539532628368 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 2.07238897772131 | bayes_pls_golite062009 |
| DNA binding | 2.05972958088217 | bayes_pls_golite062009 |
| kinase activity | 2.00903309297046 | bayes_pls_golite062009 |
| nucleic acid binding | 1.91592331431516 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.83466699022067 | bayes_pls_golite062009 |
| molecular transducer activity | 1.66598460953658 | bayes_pls_golite062009 |
| signal transducer activity | 1.66598460953658 | bayes_pls_golite062009 |
| protein kinase activity | 1.61903873760762 | bayes_pls_golite062009 |
| transferase activity | 1.45394179515146 | bayes_pls_golite062009 |
| transcription factor activity | 1.38590948364516 | bayes_pls_golite062009 |
| GTPase regulator activity | 1.12412426198961 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 1.10707685935826 | bayes_pls_golite062009 |
| myosin heavy chain kinase activity | 1.04998401151243 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.969266093401353 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.93378879973188 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.717794523788476 | bayes_pls_golite062009 |
| guanyl-nucleotide exchange factor activity | 0.6091533221871 | bayes_pls_golite062009 |
| small GTPase regulator activity | 0.442062495186646 | bayes_pls_golite062009 |
| kinase binding | 0.409606963040614 | bayes_pls_golite062009 |
| cation binding | 0.311967762495891 | bayes_pls_golite062009 |
| metal ion binding | 0.311967762495891 | bayes_pls_golite062009 |
| ion binding | 0.307697800147455 | bayes_pls_golite062009 |
| catalytic activity | 0.216721136299042 | bayes_pls_golite062009 |
|
Region A: Residues: [266-677] |
1 11 21 31 41 51
| | | | | |
1 LLRQGLQCKV CKMNVHRRCE TNVAPNCGVD ARGIAKVLAD LGVTPDKITN SGQRRKKLIA 60
61 GAESPQPASG SSPSEEDRSK SAPTSPCDQE IKELENNIRK ALSFDNRGEE HRAASSPDGQ 120
121 LMSPGENGEV RQGQAKRLGL DEFNFIKVLG KGSFGKVMLA ELKGKDEVYA VKVLKKDVIL 180
181 QDDDVDCTMT EKRILALARK HPYLTQLYCC FQTKDRLFFV MEYVNGGDLM FQIQRSRKFD 240
241 EPRSRFYAAE VTSALMFLHQ HGVIYRDLKL DNILLDAEGH CKLADFGMCK EGILNGVTTT 300
301 TFCGTPDYIA PEILQELEYG PSVDWWALGV LMYEMMAGQP PFEADNEDDL FESILHDDVL 360
361 YPVWLSKEAV SILKAFMTKN PHKRLGCVAS QNGEDAIKQH PFFKEIDWVL LE
|
| Detection Method: | |
| Confidence: | 47.0 |
| Match: | 2ozoA |
| Description: | No description for 2ozoA was found. |
|
Region A: Residues: [678-737] |
1 11 21 31 41 51
| | | | | |
1 QKKIKPPFKP RIKTKRDVNN FDQDFTREEP VLTLVDEAIV KQINQEEFKG FSYFGEDLMP 60
61
|
| Detection Method: | |
| Confidence: | 82.0 |
| Match: | 2i0eA |
| Description: | No description for 2i0eA was found. |
