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View Structure Prediction Details

Protein: SLC30A4
Organism: Homo sapiens
Length: 429 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SLC30A4.

Description E-value Query
Range
Subject
Range
gi|114656820 - gi|114656820|ref|XP_510375.2| PREDICTED: solute carrier family 30 (zinc transporter), member 4 isofo...
3.0E-99 [1..429] [1..429]
gi|74000518 - gi|74000518|ref|XP_544664.2| PREDICTED: similar to solute carrier family 30 (zinc transporter), memb...
4.0E-99 [7..429] [163..584]
SLC30A4 - solute carrier family 30 (zinc transporter), member 4
1.0E-98 [1..429] [1..429]
ZNT4_RAT - Zinc transporter 4 OS=Rattus norvegicus GN=Slc30a4 PE=2 SV=1
6.0E-97 [1..428] [1..429]
ZNT4_MOUSE - Zinc transporter 4 OS=Mus musculus GN=Slc30a4 PE=2 SV=1
3.0E-93 [1..428] [1..429]
gi|147900610, gi... - gi|52139072|gb|AAH82626.1| Slc30a4 protein [Xenopus laevis], gi|147900610|ref|NP_001087971.1| solute...
1.0E-71 [7..426] [8..411]
CE03664 - WBGene00011821 cobalt uptake like protein status:Predicted TR:Q22541 protein_id:CAA92193.1
3.0E-70 [72..428] [34..381]

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Predicted Domain #1
Region A:
Residues: [1-100]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGSGAWKRL KSMLRKDDAP LFLNDTSAFD FSDEAGDEGL SRFNKLRVVV ADDGSEAPER  60
   61 PVNGAHPTLQ ADDDSLLDQD LPLTNSQLSL KVDSCDNCSK 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [101-429]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QREILKQRKV KARLTIAAVL YLLFMIGELV GGYIANSLAI MTDALHMLTD LSAIILTLLA  60
   61 LWLSSKSPTK RFTFGFHRLE VLSAMISVLL VYILMGFLLY EAVQRTIHMN YEINGDIMLI 120
  121 TAAVGVAVNV IMGFLLNQSG HRHSHSHSLP SNSPTRGSGC ERNHGQDSLA VRAAFVHALG 180
  181 DLVQSVGVLI AAYIIRFKPE YKIADPICTY VFSLLVAFTT FRIIWDTVVI ILEGVPSHLN 240
  241 VDYIKEALMK IEDVYSVEDL NIWSLTSGKS TAIVHIQLIP GSSSKWEEVQ SKANHLLLNT 300
  301 FGMYRCTIQL QSYRQEVDRT CANCQSSSP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 54.522879
Match: 2qfiA
Description: No description for 2qfiA was found.

Predicted functions:

Term Confidence Notes
cation transmembrane transporter activity 6.3253503604398 bayes_pls_golite062009
ion transmembrane transporter activity 6.22189384650962 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 5.82185991246167 bayes_pls_golite062009
transporter activity 4.27173462293249 bayes_pls_golite062009
transmembrane transporter activity 4.18558383943492 bayes_pls_golite062009
substrate-specific transporter activity 3.94511592355578 bayes_pls_golite062009
metal ion transmembrane transporter activity 2.43294134632841 bayes_pls_golite062009
transition metal ion transmembrane transporter activity 2.32644140472297 bayes_pls_golite062009
efflux transmembrane transporter activity 1.98656970252979 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 1.95281540802467 bayes_pls_golite062009
cation channel activity 1.55011961058299 bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity 1.31663166812163 bayes_pls_golite062009
binding 1.27456652114636 bayes_pls_golite062009
ion channel activity 1.01093555209783 bayes_pls_golite062009
passive transmembrane transporter activity 0.963824080292546 bayes_pls_golite062009
channel activity 0.963824080292546 bayes_pls_golite062009
substrate-specific channel activity 0.948079854416241 bayes_pls_golite062009
cadmium ion transmembrane transporter activity 0.661906409169955 bayes_pls_golite062009
active transmembrane transporter activity 0.490905558612378 bayes_pls_golite062009
iron ion transmembrane transporter activity 0.376948884172728 bayes_pls_golite062009
protein binding 0.311357063667067 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle