YRC Public Data Repository - Protein Structure Prediction

Protein:	PSMD10
Organism:	Homo sapiens
Length:	226 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PSMD10.

Description	E-value	Query Range	Subject Range
gi\|115433911, gi... - gi\|115433911\|ref\|XP_001217610.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	2.0E-67	[2..224]	[931..1153]
gi\|66847484, gi\|... - gi\|70990006\|ref\|XP_749852.1\| Pfs, NACHT and Ankyrin domain protein [Aspergillus fumigatus Af293], gi...	3.0E-67	[5..224]	[1249..1468]
gi\|108868779, gi... - gi\|157106769\|ref\|XP_001649474.1\| ankyrin 2,3/unc44 [Aedes aegypti], gi\|108868779\|gb\|EAT33004.1\| anky...	8.0E-67	[4..224]	[16..236]
gi\|116202685, gi... - gi\|88177745\|gb\|EAQ85213.1\| hypothetical protein CHGG_09227 [Chaetomium globosum CBS 148.51], gi\|1162...	7.0E-66	[4..224]	[833..1053]
gi\|115621182, gi... - gi\|115951148\|ref\|XP_001197526.1\| PREDICTED: similar to ankyrin 2,3/unc44 [Strongylocentrotus purpura...	9.0E-66	[2..224]	[97..328]
gi\|99034632 - gi\|99034632\|ref\|ZP_01314584.1\| hypothetical protein Wendoof_01000602 [Wolbachia endosymbiont of Dros...	1.0E-65	[2..224]	[595..816]
gi\|50760226 - gi\|50760226\|ref\|XP_425812.1\| PREDICTED: similar to neural cell adhesion molecule long domain form pr...	4.0E-65	[7..225]	[4187..4405]

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Predicted Domain #1

Region A:
Residues: [1-226]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEGCVSNLMV CNLAYSGKLE ELKESILADK SLATRTDQDS RTALHWACSA GHTEIVEFLL  60
   61 QLGVPVNDKD DAGWSPLHIA ASAGRDEIVK ALLGKGAQVN AVNQNGCTPL HYAASKNRHE 120
  121 IAVMLLEGGA NPDAKDHYEA TAMHRAAAKG NLKMIHILLY YKASTNIQDT EGNTPLHLAC 180
  181 DEERVEEAKL LVSQGASIYI ENKEEKTPLQ VAKGGLGLIL KRMVEG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.69897
Match:	1tr4A
Description:	Solution structure of human oncogenic protein gankyrin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	2.43232200709693	bayes_pls_golite062009
binding	2.41068257517762	bayes_pls_golite062009
structural molecule activity	2.02593487630436	bayes_pls_golite062009
cytoskeletal protein binding	1.93050618316228	bayes_pls_golite062009
protein binding	1.54890102798695	bayes_pls_golite062009
structural constituent of cytoskeleton	1.29094941611102	bayes_pls_golite062009
ubiquitin-protein ligase activity	1.23556500721571	bayes_pls_golite062009
small conjugating protein ligase activity	1.13900029077952	bayes_pls_golite062009
enzyme binding	0.60140077251711	bayes_pls_golite062009
transcription regulator activity	0.327689573161126	bayes_pls_golite062009
nucleic acid binding	0.280340492381105	bayes_pls_golite062009
acid-amino acid ligase activity	0.247967126091535	bayes_pls_golite062009
actin binding	0.168912685840912	bayes_pls_golite062009
cyclin-dependent protein kinase regulator activity	0.0462605323512499	bayes_pls_golite062009
DNA binding	0.0016834194928852	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: