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View Structure Prediction Details

Protein: COX5B
Organism: Homo sapiens
Length: 129 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COX5B.

Description E-value Query
Range
Subject
Range
gi|74152883, gi|... - gi|74199859|dbj|BAE20757.1| unnamed protein product [Mus musculus], gi|74152883|dbj|BAE22451.1| unna...
9.0E-57 [1..129] [1..129]
gi|60824360 - gi|60824360|gb|AAX36677.1| cytochrome c oxidase subunit Vb [synthetic construct]
gi|49456415 - gi|49456415|emb|CAG46528.1| COX5B [Homo sapiens]
2.0E-55 [1..129] [1..129]
gi|60833885 - gi|60833885|gb|AAX37069.1| cytochrome c oxidase subunit Vb [synthetic construct]
2.0E-55 [1..129] [1..129]
COX5B_RAT - Cytochrome c oxidase subunit 5B, mitochondrial OS=Rattus norvegicus GN=Cox5b PE=1 SV=2
2.0E-55 [1..129] [1..129]
COX5B_BOVIN - Cytochrome c oxidase subunit 5B, mitochondrial OS=Bos taurus GN=COX5B PE=1 SV=2
4.0E-54 [1..129] [1..129]

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Predicted Domain #1
Region A:
Residues: [1-129]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASRLLRGAG TLAAQALRAR GPSGAAAMRS MASGGGVPTD EEQATGLERE IMLAAKKGLD  60
   61 PYNVLAPKGA SGTREDPNLV PSISNKRIVG CICEEDNTSV VWFWLHKGEA QRCPRCGAHY 120
  121 KLVPQQLAH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.69897
Match: 1occF
Description: Cytochrome c oxidase Subunit F
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytochrome-c oxidase activity 0.942365217032167 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors 0.942365217032167 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor 0.942365217032167 bayes_pls_golite062009
binding 0.925615758639096 bayes_pls_golite062009
heme-copper terminal oxidase activity 0.706848307362399 bayes_pls_golite062009
cation transmembrane transporter activity 0.0832654869651861 bayes_pls_golite062009
ion transmembrane transporter activity 0.00798941779972262 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle