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View Structure Prediction Details

Protein: FABP6
Organism: Homo sapiens
Length: 128 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FABP6.

Description E-value Query
Range
Subject
Range
gi|114658435 - gi|114658435|ref|XP_001142851.1| PREDICTED: similar to cellular retinoic acid-binding protein; CRABP...
9.0E-40 [2..126] [247..380]
FABPH_RAT - Fatty acid-binding protein, heart OS=Rattus norvegicus GN=Fabp3 PE=1 SV=2
2.0E-36 [2..128] [4..133]
FABPH_MOUSE - Fatty acid-binding protein, heart OS=Mus musculus GN=Fabp3 PE=1 SV=5
2.0E-36 [2..128] [4..133]
gi|226536920, gi... - gi|39939390|gb|AAR32738.1| fatty acid-binding protein [Capra hircus], gi|226536920|gb|ACO72586.1| he...
2.0E-36 [2..128] [4..133]
FABPH_PIG - Fatty acid-binding protein, heart OS=Sus scrofa GN=FABP3 PE=2 SV=3
4.0E-36 [2..128] [4..133]
FABPH_ICTTR - Fatty acid-binding protein, heart OS=Ictidomys tridecemlineatus GN=FABP3 PE=2 SV=3
5.0E-36 [2..128] [4..133]
gi|1869803, gi|4... - gi|48145851|emb|CAG33148.1| FABP3 [Homo sapiens], gi|1869803|emb|CAA71305.1| mammary-derived growth ...
7.0E-36 [2..128] [4..133]
gi|60653429, gi|... - gi|60653429|gb|AAX29409.1| fatty acid binding protein 3 muscle and heart [synthetic construct], gi|3...
9.0E-36 [2..128] [4..133]

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Predicted Domain #1
Region A:
Residues: [1-128]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFTGKFEME SEKNYDEFMK LLGISSDVIE KARNFKIVTE VQQDGQDFTW SQHYSGGHTM  60
   61 TNKFTVGKES NIQTMGGKTF KATVQMEGGK LVVNFPNYHQ TSEIVGDKLV EVSTIGGVTY 120
  121 ERVSKRLA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.045757
Match: 1o1uA
Description: Ileal lipid-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
long-chain fatty acid transporter activity 5.31242454679135 bayes_pls_golite062009
fatty acid transporter activity 5.05947161650978 bayes_pls_golite062009
lysophospholipid transporter activity 4.87368345652673 bayes_pls_golite062009
lipid transporter activity 4.30505384117861 bayes_pls_golite062009
binding 2.93830472620404 bayes_pls_golite062009
bile acid binding 1.56765865943557 bayes_pls_golite062009
transcription regulator activity 1.48205265725428 bayes_pls_golite062009
protein binding 1.23450129884619 bayes_pls_golite062009
retinol transporter activity 1.2139173346293 bayes_pls_golite062009
prostaglandin-D synthase activity 1.18764036773412 bayes_pls_golite062009
lipid binding 0.936781587098929 bayes_pls_golite062009
fatty acid binding 0.761923641769607 bayes_pls_golite062009
retinoid binding 0.451050759082675 bayes_pls_golite062009
isoprenoid binding 0.394662096985878 bayes_pls_golite062009

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