YRC Public Data Repository - Protein Structure Prediction

Protein:	PSF3
Organism:	Saccharomyces cerevisiae
Length:	194 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PSF3.

Description	E-value	Query Range	Subject Range
PSF3_YEAST - DNA replication complex GINS protein PSF3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G... PSF3 - Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication orig...	2.0E-65	[1..194]	[1..194]
PSF3_NEUCR - DNA replication complex GINS protein psf3 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS... PSF3_NEUCR - DNA replication complex GINS protein psf-3 OS=Neurospora crassa GN=psf-3 PE=3 SV=1	2.0E-61	[1..191]	[1..212]
PSF3_ASHGO - DNA replication complex GINS protein PSF3 OS=Ashbya gossypii GN=PSF3 PE=3 SV=1 PSF3_ASHGO - DNA replication complex GINS protein PSF3 OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC ...	2.0E-56	[1..194]	[1..185]
PSF3_GIBZE - DNA replication complex GINS protein PSF3 OS=Gibberella zeae GN=PSF3 PE=3 SV=1 PSF3_GIBZE - DNA replication complex GINS protein PSF3 OS=Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 907...	7.0E-56	[1..193]	[1..175]
PSF3_CANAL - DNA replication complex GINS protein PSF3 OS=Candida albicans GN=PSF3 PE=3 SV=1 PSF3_CANAL - DNA replication complex GINS protein PSF3 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PSF...	3.0E-50	[2..194]	[4..177]
psf3 (reserved) - GINS complex subunit Psf3 PSF3_SCHPO - DNA replication complex GINS protein psf3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=...	3.0E-46	[1..190]	[1..161]
gi\|46096083, gi\|... - gi\|71003624\|ref\|XP_756478.1\| hypothetical protein UM00331.1 [Ustilago maydis 521], ref\|XP_397946.1\| ...	6.0E-45	[3..192]	[5..212]
GINS3 - GINS complex subunit 3 (Psf3 homolog)	3.0E-44	[3..190]	[19..189]
gi\|38566626, gi\|... - gi\|98961791\|gb\|ABF59225.1\| unknown protein [Arabidopsis thaliana], gi\|40824111\|gb\|AAR92348.1\| At1g19...	6.0E-44	[3..190]	[4..164]
PSF3_MOUSE - DNA replication complex GINS protein PSF3 OS=Mus musculus GN=Gins3 PE=2 SV=1	1.0E-43	[3..190]	[19..189]

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Predicted Domain #1

Region A:
Residues: [1-194]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGYYDIDDVL ADGTEFPCKF QYDIPGLGYL ENNPGRPITK NTKLSLPLWL ARILAIVGGD  60
   61 EALVDEEPVP FVELLPPDMF STKVMNAIKT DPVALDLHSI NSHFFSLAIK WIMLFSEKEL 120
  121 ANVVSELLLQ RAQELNHHAS SLSIDLNADS TGKNSANTNI ATSTFLLKLE EMEKEIYKKS 180
  181 HESYKDTKRW MFKK

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	9.337242
Match:	PF06425.1
Description:	No description for PF06425.1 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
3'-5' DNA helicase activity	3.30007058745861	bayes_pls_golite062009
DNA helicase activity	2.7662250039458	bayes_pls_golite062009
binding	1.27082628880017	bayes_pls_golite062009
transcription regulator activity	1.2336233528067	bayes_pls_golite062009
helicase activity	1.2110072302388	bayes_pls_golite062009
transcription elongation regulator activity	0.37490315580617	bayes_pls_golite062009
catalytic activity	0.161911144249814	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: