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View Structure Prediction Details

Protein: FUR1
Organism: Saccharomyces cerevisiae
Length: 216 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FUR1.

Description E-value Query
Range
Subject
Range
UPP_LACLM - Uracil phosphoribosyltransferase OS=Lactococcus lactis subsp. cremoris (strain MG1363) GN=upp PE=3 S...
gi|599847 - gi|599847|emb|CAA51755.1| uracil phosphoribosyltransferase [Lactococcus lactis]
UPP_LACLC - Uracil phosphoribosyltransferase (EC 2.4.2.9) (UMP pyrophosphorylase) (UPRTase) - Lactococcus lactis...
258.0 [0..6] [215..1]

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Predicted Domain #1
Region A:
Residues: [1-216]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSEPFKNVY LLPQTNQLLG LYTIIRNKNT TRPDFIFYSD RIIRLLVEEG LNHLPVQKQI  60
   61 VETDTNENFE GVSFMGKICG VSIVRAGESM EQGLRDCCRS VRIGKILIQR DEETALPKLF 120
  121 YEKLPEDISE RYVFLLDPML ATGGSAIMAT EVLIKRGVKP ERIYFLNLIC SKEGIEKYHA 180
  181 AFPEVRIVTG ALDRGLDENK YLVPGLGDFG DRYYCV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.30103
Match: 1bd3D
Description: Uracil PRTase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
uracil phosphoribosyltransferase activity 3.97944228585882 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 3.91023158228049 bayes_pls_golite062009
adenine phosphoribosyltransferase activity 3.07502596276449 bayes_pls_golite062009
transferase activity 2.73727660668741 bayes_pls_golite062009
hypoxanthine phosphoribosyltransferase activity 2.67945744445872 bayes_pls_golite062009
transferase activity, transferring pentosyl groups 2.53679639481311 bayes_pls_golite062009
catalytic activity 2.30431811394775 bayes_pls_golite062009
ribose phosphate diphosphokinase activity 0.947697983706416 bayes_pls_golite062009
diphosphotransferase activity 0.749909396904601 bayes_pls_golite062009
binding 0.730385736169604 bayes_pls_golite062009
nucleic acid binding 0.552133387792911 bayes_pls_golite062009
DNA binding 0.439741935655503 bayes_pls_golite062009
transcription regulator activity 0.396538943915776 bayes_pls_golite062009
amidophosphoribosyltransferase activity 0.360901350940423 bayes_pls_golite062009
purine binding 0.358545436706029 bayes_pls_golite062009
orotate phosphoribosyltransferase activity 0.148898393751978 bayes_pls_golite062009
nucleobase binding 0.0803493215714011 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle