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View Structure Prediction Details

Protein: AXL1
Organism: Saccharomyces cerevisiae
Length: 1208 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AXL1.

Description E-value Query
Range
Subject
Range
gi|190408049 - gi|190408049|gb|EDV11314.1| hypothetical protein SCRG_02600 [Saccharomyces cerevisiae RM11-1a]
AXL1_YEAST - Putative protease AXL1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AXL1 PE=1 SV=2
gi|151942899 - gi|151942899|gb|EDN61245.1| axial budding-related protein [Saccharomyces cerevisiae YJM789]
AXL1 - Haploid specific endoprotease that performs one of two N-terminal cleavages during maturation of a-f...
0.0 [1..1208] [1..1208]
IDE1_ARATH - Insulin-degrading enzyme-like 1, peroxisomal OS=Arabidopsis thaliana GN=PXM16 PE=2 SV=1
0.0 [14..1092] [15..936]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [14..1092] [17..961]
gi|50938485, gi|... - gi|50938485|ref|XP_478770.1| putative insulin degrading enzyme [Oryza sativa (japonica cultivar-grou...
0.0 [4..1087] [21..947]
gi|15485612 - gi|15485612|emb|CAC67408.1| insulin degrading enzyme [Solanum lycopersicum]
0.0 [14..1092] [14..935]

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Predicted Domain #1
Region A:
Residues: [1-161]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLREVTNYE VSFYIPLSYS NRTHKVCKLP NGILALIISD PTDTSSSCSL TVCTGSHNDP  60
   61 KDIAGLAHLC EHMILSAGSK KYPDPGLFHT LIAKNNGSQN AFTTGEQTTF YFELPNTQNN 120
  121 GEFTFESILD VFASFFKEPL FNPLLISKEI YAIQSEHEGN I

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [180-260]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HPFSRFSTGN IHSLSSIPQL KKIKLKSSLN TYFENNFFGE NITLCIRGPQ SVNILTKLAL  60
   61 SKFGDIKPKS AVKERSISIR T

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [441-471]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSSEDLPMEE CSKLSGILQD DLECLTPPNI F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 128.9794
Match: 1hr6B_
Description: Mitochondrial processing peptidase (MPP) beta chain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [162-179]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSTTKIFYHA ARILANPD

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [261-440]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSFRRSKSLK KRQDSSKNDY SDLKTFKILN TTWEKKYKNT MCFQQFPECN SIFINSNKVP  60
   61 IMRLLFPVSD KNTRFTKDDI KIYSHLWCEL FGDESPGSLS YYLASKGWLT GCFAFTSEFA 120
  121 IGDIGLILEL ELTNSGWENI KRITTIVLNR LLPSFYVMNI DYLITFLKEQ NLIDLVSFLY 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 128.9794
Match: 1hr6B_
Description: Mitochondrial processing peptidase (MPP) beta chain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [472-568]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGFKSLIEID DPNIEKYENT KANIQWWTGQ AIKFQNFLKS FMNHDNMRLL LLGNIKSGNI  60
   61 FDKMKNKSDI CTDFFYEFEY YTANVHLASD NKFHSNS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [569-1011]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SYEFNFPTGN LFLPDCVSDP LKLQQLFLEC SLKSKFATLR PQIYSEPTRT KPQLVSENQN  60
   61 YEMWILKEDP NFASDNKSVV SFEVLGLGIK PSPEATIHLE VLAQALFIIT SSFLYPALRI 120
  121 GYTYEIASSS KGNVTLRFTI SGFPEGVFTI VKTFVDTLKL IATDPTFLSK DTLRKARILV 180
  181 RNKYKNASSD NCVKLASVGL LIVLEKYIWT LEDRINALEL TELESFEKFC FLFWRNPKHL 240
  241 VLFMQGSLEY ADAINRYLNN NFTQHLKISN EGSKPTIRLY PPPSTKDLDQ GTNAFISYNG 300
  301 HQDDPNNSIV YFIQTAQRDD IKNLTLTFLT EYLFSLTLVP DLRNKKQIGY IVLGGLRVLT 360
  361 DTVGIHITVM SGSSGHNLET RINEYLSYLQ LQVLNRFTEF DFRRILLEPF LNLLKQNSTK 420
  421 QFEGSAGPVD LLNEIVANVQ NGD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [1012-1121]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NYTLNNKQMR QHRKVRNKIA EGRLNFQEDH EMIDISFLQK LTLKKYLAFF ESKISIYSAQ  60
   61 RSKLSIMITS PMAEKEIASR KMFLQLEAFL KINGFAIKNE DLKKIVEHSK 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1122-1208]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNPILLVKNL FTYFRRRNEV FKLGTVVLQE ILKIIGMNLK QRYGSILGFS SQDGEGQEIE  60
   61 KFWNNDTSPI VPLQELPEPN FFRKAAF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle