YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: AXL1
Organism: Saccharomyces cerevisiae
Length: 1208 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AXL1.

Description E-value Query
Range
Subject
Range
gi|190408049 - gi|190408049|gb|EDV11314.1| hypothetical protein SCRG_02600 [Saccharomyces cerevisiae RM11-1a]
AXL1_YEAST - Putative protease AXL1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AXL1 PE=1 SV=2
gi|151942899 - gi|151942899|gb|EDN61245.1| axial budding-related protein [Saccharomyces cerevisiae YJM789]
AXL1 - Haploid specific endoprotease that performs one of two N-terminal cleavages during maturation of a-f...
0.0 [1..1208] [1..1208]
IDE1_ARATH - Insulin-degrading enzyme-like 1, peroxisomal OS=Arabidopsis thaliana GN=PXM16 PE=2 SV=1
0.0 [14..1092] [15..936]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [14..1092] [17..961]
gi|50938485, gi|... - gi|50938485|ref|XP_478770.1| putative insulin degrading enzyme [Oryza sativa (japonica cultivar-grou...
0.0 [4..1087] [21..947]
gi|15485612 - gi|15485612|emb|CAC67408.1| insulin degrading enzyme [Solanum lycopersicum]
0.0 [14..1092] [14..935]

Back

Predicted Domain #1
Region A:
Residues: [1-161]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLREVTNYE VSFYIPLSYS NRTHKVCKLP NGILALIISD PTDTSSSCSL TVCTGSHNDP  60
   61 KDIAGLAHLC EHMILSAGSK KYPDPGLFHT LIAKNNGSQN AFTTGEQTTF YFELPNTQNN 120
  121 GEFTFESILD VFASFFKEPL FNPLLISKEI YAIQSEHEGN I

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [180-260]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HPFSRFSTGN IHSLSSIPQL KKIKLKSSLN TYFENNFFGE NITLCIRGPQ SVNILTKLAL  60
   61 SKFGDIKPKS AVKERSISIR T

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [441-471]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSSEDLPMEE CSKLSGILQD DLECLTPPNI F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 128.9794
Match: 1hr6B_
Description: Mitochondrial processing peptidase (MPP) beta chain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [162-179]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSTTKIFYHA ARILANPD

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [261-440]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSFRRSKSLK KRQDSSKNDY SDLKTFKILN TTWEKKYKNT MCFQQFPECN SIFINSNKVP  60
   61 IMRLLFPVSD KNTRFTKDDI KIYSHLWCEL FGDESPGSLS YYLASKGWLT GCFAFTSEFA 120
  121 IGDIGLILEL ELTNSGWENI KRITTIVLNR LLPSFYVMNI DYLITFLKEQ NLIDLVSFLY 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 128.9794
Match: 1hr6B_
Description: Mitochondrial processing peptidase (MPP) beta chain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [472-568]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGFKSLIEID DPNIEKYENT KANIQWWTGQ AIKFQNFLKS FMNHDNMRLL LLGNIKSGNI  60
   61 FDKMKNKSDI CTDFFYEFEY YTANVHLASD NKFHSNS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.425 c.47.1 Thioredoxin-like
View Download 0.289 c.3.1 FAD/NAD(P)-binding domain
View Download 0.398 d.39.1 Dynein light chain 8 (DLC8)
View Download 0.300 c.13.2 Anti-sigma factor antagonist SpoIIaa
View Download 0.257 c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View Download 0.253 d.68.3 SirA-like
View Download 0.249 c.30.1 PreATP-grasp domain
View Download 0.235 a.59.1 PAH2 domain
View Download 0.226 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.222 c.47.1 Thioredoxin-like
View Download 0.218 c.23.4 Succinyl-CoA synthetase domains

Predicted Domain #4
Region A:
Residues: [569-1011]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SYEFNFPTGN LFLPDCVSDP LKLQQLFLEC SLKSKFATLR PQIYSEPTRT KPQLVSENQN  60
   61 YEMWILKEDP NFASDNKSVV SFEVLGLGIK PSPEATIHLE VLAQALFIIT SSFLYPALRI 120
  121 GYTYEIASSS KGNVTLRFTI SGFPEGVFTI VKTFVDTLKL IATDPTFLSK DTLRKARILV 180
  181 RNKYKNASSD NCVKLASVGL LIVLEKYIWT LEDRINALEL TELESFEKFC FLFWRNPKHL 240
  241 VLFMQGSLEY ADAINRYLNN NFTQHLKISN EGSKPTIRLY PPPSTKDLDQ GTNAFISYNG 300
  301 HQDDPNNSIV YFIQTAQRDD IKNLTLTFLT EYLFSLTLVP DLRNKKQIGY IVLGGLRVLT 360
  361 DTVGIHITVM SGSSGHNLET RINEYLSYLQ LQVLNRFTEF DFRRILLEPF LNLLKQNSTK 420
  421 QFEGSAGPVD LLNEIVANVQ NGD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [1012-1121]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NYTLNNKQMR QHRKVRNKIA EGRLNFQEDH EMIDISFLQK LTLKKYLAFF ESKISIYSAQ  60
   61 RSKLSIMITS PMAEKEIASR KMFLQLEAFL KINGFAIKNE DLKKIVEHSK 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.471 0.373 axial cellular bud site selection a.1.1 Globin-like
View Download 0.764 0.026 axial cellular bud site selection d.68.1 Translation initiation factor IF3, C-terminal domain
View Download 0.403 0.023 axial cellular bud site selection d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.420 0.009 axial cellular bud site selection d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.444 N/A N/A d.58.47 Hypothetical protein VC0424
View Download 0.340 N/A N/A d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.317 N/A N/A d.141.1 Ribosomal protein L6
View Download 0.314 N/A N/A d.68.4 YhbY-like
View Download 0.313 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.279 N/A N/A d.74.1 Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH)
View Download 0.264 N/A N/A d.155.1 Pyruvoyl-dependent histidine and arginine decarboxylases
View Download 0.259 N/A N/A d.212.1 TolA/TonB C-terminal domain
View Download 0.251 N/A N/A c.97.1 Cytidine deaminase-like
View Download 0.249 N/A N/A d.58.12 eEF-1beta-like
View Download 0.242 N/A N/A a.54.1 Domain of early E2A DNA-binding protein, ADDBP
View Download 0.230 N/A N/A d.129.1 TATA-box binding protein-like
View Download 0.227 N/A N/A d.58.17 Metal-binding domain
View Download 0.220 N/A N/A d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.217 N/A N/A d.109.1 Actin depolymerizing proteins
View Download 0.212 N/A N/A c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.204 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.201 N/A N/A a.118.8 TPR-like

Predicted Domain #6
Region A:
Residues: [1122-1208]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNPILLVKNL FTYFRRRNEV FKLGTVVLQE ILKIIGMNLK QRYGSILGFS SQDGEGQEIE  60
   61 KFWNNDTSPI VPLQELPEPN FFRKAAF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.506 a.4.5 "Winged helix" DNA-binding domain
View Download 0.586 a.4.1 Homeodomain-like
View Download 0.650 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.578 a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.504 a.4.5 "Winged helix" DNA-binding domain
View Download 0.477 a.4.5 "Winged helix" DNA-binding domain
View Download 0.445 a.74.1 Cyclin-like
View Download 0.435 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.434 a.4.1 Homeodomain-like
View Download 0.419 d.15.2 CAD & PB1 domains
View Download 0.412 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.404 a.156.1 S13-like H2TH domain
View Download 0.403 a.4.5 "Winged helix" DNA-binding domain
View Download 0.358 a.74.1 Cyclin-like
View Download 0.349 a.112.1 Description not found.
View Download 0.345 a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.334 d.15.1 Ubiquitin-like
View Download 0.327 c.47.1 Thioredoxin-like
View Download 0.325 a.4.1 Homeodomain-like
View Download 0.316 d.15.6 Superantigen toxins, C-terminal domain
View Download 0.309 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.308 d.234.1 Proguanylin
View Download 0.298 a.46.1 Methionine synthase domain
View Download 0.298 a.64.1 Saposin
View Download 0.294 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.292 a.4.1 Homeodomain-like
View Download 0.289 a.21.1 HMG-box
View Download 0.280 a.4.12 TrpR-like
View Download 0.277 a.64.2 Bacteriocin AS-48
View Download 0.277 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.260 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.256 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.249 d.39.1 Dynein light chain 8 (DLC8)
View Download 0.248 a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.242 a.4.5 "Winged helix" DNA-binding domain
View Download 0.241 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.239 c.47.1 Thioredoxin-like
View Download 0.238 a.4.5 "Winged helix" DNA-binding domain
View Download 0.235 a.39.1 EF-hand
View Download 0.228 a.28.2 Colicin E immunity proteins
View Download 0.226 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.224 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.224 a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.217 a.144.1 PABC (PABP) domain
View Download 0.212 a.4.5 "Winged helix" DNA-binding domain
View Download 0.212 a.39.1 EF-hand
View Download 0.208 a.101.1 Uteroglobin-like
View Download 0.205 d.53.1 Ribosomal protein S3 C-terminal domain
View Download 0.202 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle