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View Structure Prediction Details

Protein: RGC1
Organism: Saccharomyces cerevisiae
Length: 1083 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RGC1.

Description E-value Query
Range
Subject
Range
ASK10_YEAST - Activator of SKN7 protein 10 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ASK10 PE=1 ...
gi|207345134 - gi|207345134|gb|EDZ72053.1| YGR097Wp-like protein [Saccharomyces cerevisiae AWRI1631]
ASK10 - Component of the RNA polymerase II holoenzyme, phosphorylated in response to oxidative stress; has a...
0.0 [29..1082] [10..1079]
gi|85093000 - gi|85093000|ref|XP_959607.1| hypothetical protein NCU02425 [Neurospora crassa OR74A]
gi|28921051, gi|... - gi|32421515|ref|XP_331201.1| hypothetical protein [Neurospora crassa], gi|28921051|gb|EAA30371.1| co...
3.0E-91 [230..552] [164..465]
SLM1_SCHPO - Cytoskeletal signaling protein slm1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=slm1 P...
SPAC637.13c - cytoskeletal signaling protein
2.0E-89 [268..574] [87..380]

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Predicted Domain #1
Region A:
Residues: [1-475]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDYFTFPKQ ENGGISKQPA TPGSTRSSSR NLELPKNYRS FGGSSDELAS MYSADSQYLM  60
   61 DMIPDSLTLK NEPASGNTQM NGPDGKENKD IKLDEYILPK TDPRSPYYIN MPIPKKLPKS 120
  121 EGKARAKQKV NRADPSDLDV ENIYETSGEF VREYPTDILI DRFHKWKKIL KSLIAYFREA 180
  181 AYSQEQIARI NYQMKNAVKF AFLTDLEDET NKLVDPSISK LPTKKPQPVP LAAQKLDSKY 240
  241 DTDVEQPQSI QSVPSEEVAS ASSGFMKFGS GSIQDIQVIL KKYHLSLGSQ QYKISKEILA 300
  301 YIIPKLTDLR KDLTTKMKEI KELNGDFKTN IGEHIKITSR LLNKYIASVK LLDEASTSGD 360
  361 KQGEKLKPKH DPYLLKLQLD LQLKRQLLEE NYLREAFLNL QSAALQLEKI VYSKIQSALQ 420
  421 RYSALIDSEA RLMIKNLCHE LQQGILSRPP AVEWDNFVSH HPTCLMNLKS TDPPP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [476-747]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPRRLSDIVY PNMKSPLAKC IRVGYLLKKT ESSKSFTKGY FVLTTNYLHE FKSSDFFLDS  60
   61 KSPRSKNKPV VEQSDISRVN KDGTNAGSHP SSKGTQDPKL TKRRKGLSSS NLYPISSLSL 120
  121 NDCSLKDSTD STFVLQGYAS YHSPEDTCTK ESSTTSDLAC PTKTLASNKG KHQRTPSALS 180
  181 MVSVPKFLKS SSVPKEQKKA KEEANINKKS ICEKRVEWTF KIFSASLEPT PEESKNFKKW 240
  241 VQDIKALTSF NSTQERSNFI EEKILKSRNH NN

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 6.958607
Match: PF00169
Description: PH domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [748-1083]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKSSQRSKNS TYITPVDSFV NLSEKVTPSS SVTTLNTRKR ANRPRYIDIP KSANMNAGAM  60
   61 NSVYRSKVNT PAIDENGNLA IVGETKNSAP QNGMSYTIRT PCKSPYSPYT GEGMLYNRSA 120
  121 DNLMASSSRK ASAPGEVPQI AVSNHGDEAI IPASAYSDSS HKSSRASSVA SIHNQRVDFY 180
  181 PSPLMNLPGV SPSCLALDGN ANGYFGIPLN CNSEARRGSD LSPFEMESPL FEENRTQNCS 240
  241 GSRKSSACHI PHQCGPRKEG NDSRLIYGNE KGASQSRLTL KEPLTSKGVE APYSSLKKTY 300
  301 SAENVPLTST VSNDKSLHSR KEGSTNTVPA TSASSK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [469-805]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSTDPPPQPR RLSDIVYPNM KSPLAKCIRV GYLLKKTESS KSFTKGYFVL TTNYLHEFKS  60
   61 SDFFLDSKSP RSKNKPVVEQ SDISRVNKDG TNAGSHPSSK GTQDPKLTKR RKGLSSSNLY 120
  121 PISSLSLNDC SLKDSTDSTF VLQGYASYHS PEDTCTKESS TTSDLACPTK TLASNKGKHQ 180
  181 RTPSALSMVS VPKFLKSSSV PKEQKKAKEE ANINKKSICE KRVEWTFKIF SASLEPTPEE 240
  241 SKNFKKWVQD IKALTSFNST QERSNFIEEK ILKSRNHNNG KSSQRSKNST YITPVDSFVN 300
  301 LSEKVTPSSS VTTLNTRKRA NRPRYIDIPK SANMNAG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.982
Match: 1qqgA
Description: Insulin receptor substrate 1, IRS-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.92972815841164 bayes_pls_golite062009
protein binding 1.26119545864643 bayes_pls_golite062009
hydrolase activity 0.0325416327974032 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [806-966]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AMNSVYRSKV NTPAIDENGN LAIVGETKNS APQNGMSYTI RTPCKSPYSP YTGEGMLYNR  60
   61 SADNLMASSS RKASAPGEVP QIAVSNHGDE AIIPASAYSD SSHKSSRASS VASIHNQRVD 120
  121 FYPSPLMNLP GVSPSCLALD GNANGYFGIP LNCNSEARRG S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [967-1083]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLSPFEMESP LFEENRTQNC SGSRKSSACH IPHQCGPRKE GNDSRLIYGN EKGASQSRLT  60
   61 LKEPLTSKGV EAPYSSLKKT YSAENVPLTS TVSNDKSLHS RKEGSTNTVP ATSASSK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle