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View Structure Prediction Details

Protein: SPE3
Organism: Saccharomyces cerevisiae
Length: 293 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPE3.

Description E-value Query
Range
Subject
Range
gi|190690763, gi... - gi|190690763|gb|ACE87156.1| spermidine synthase protein [synthetic construct], gi|190689401|gb|ACE86...
SRM - spermidine synthase
8.0E-88 [4..293] [10..299]
SPD1_ARATH - Spermidine synthase 1 OS=Arabidopsis thaliana GN=SPDSYN1 PE=1 SV=1
3.0E-87 [8..292] [41..329]
SPEE_MOUSE - Spermidine synthase OS=Mus musculus GN=Srm PE=1 SV=1
5.0E-87 [7..293] [13..299]
gi|13384156, gi|... - gi|16758208|ref|NP_445916.1| spermidine synthase [Rattus norvegicus], gi|13384156|gb|AAK21288.1|AF33...
7.0E-87 [7..293] [13..299]
SPD2_PEA - Spermidine synthase 2 OS=Pisum sativum GN=SPDSYN2 PE=2 SV=1
2.0E-86 [8..292] [48..337]
gi|16024930 - gi|16024930|gb|AAL11443.1| spermidine synthase [Aspergillus nidulans]
gi|49085398, gi|... - gi|67516811|ref|XP_658291.1| SPEE_NEUCR Spermidine synthase (Putrescine aminopropyltransferase) (SPD...
4.0E-86 [4..292] [3..290]
gi|23495354 - gi|23495354|dbj|BAC20171.1| spermidine synthase [Malus x domestica]
6.0E-86 [6..293] [44..331]

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Predicted Domain #1
Region A:
Residues: [1-65]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQEITHPTI VDGWFREISD TMWPGQAMTL KVEKVLHHEK SKYQDVLIFK STTYGNVLVL  60
   61 DNVIQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 589.39794
Match: 1inlA_
Description: Spermidine synthase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
spermidine synthase activity 2.31131562815571 bayes_pls_golite062009
transferase activity 1.77671966857605 bayes_pls_golite062009
transcription regulator activity 1.61435611638306 bayes_pls_golite062009
DNA binding 1.53375495589674 bayes_pls_golite062009
nucleic acid binding 1.31440474302645 bayes_pls_golite062009
catalytic activity 1.25333584501255 bayes_pls_golite062009
binding 0.976078016260105 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 0.837368219068434 bayes_pls_golite062009
N-methyltransferase activity 0.69697643153076 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 0.644010137949015 bayes_pls_golite062009
methyltransferase activity 0.635463629299812 bayes_pls_golite062009
protein methyltransferase activity 0.57386401278889 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [66-293]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATERDEFAYQ EMIAHLALNS HPNPKKVLVI GGGDGGVLRE VVKHDSVEEA WLCDIDEAVI  60
   61 RLSKEYLPEM AASYSHPKVK THIGDGFQFL RDYQNTFDVI ITDSSDPEGP AETLFQKEYF 120
  121 QLLNSALTEK GVITTQAESM WIHLPIIKDL KKACSEVFPV AEYSFVTIPT YPTGTIGFMV 180
  181 CSKDKTCNVK KPLREISDEK EAELYRYYNK KIHEASFVLP TWAAKELN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 589.39794
Match: 1inlA_
Description: Spermidine synthase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle