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View Structure Prediction Details

Protein: ATG11
Organism: Saccharomyces cerevisiae
Length: 1178 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ATG11.

Description E-value Query
Range
Subject
Range
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
0.0 [29..1120] [808..1928]
MYH2_HORSE - Myosin-2 OS=Equus caballus GN=MYH2 PE=2 SV=1
0.0 [29..1120] [808..1928]
gi|42476190, gi|... - gi|42476190|ref|NP_060004.2| myosin, heavy polypeptide 2, skeletal muscle, adult [Homo sapiens], gi|...
0.0 [29..1120] [812..1932]
MYH2_BOVIN - Myosin-2 OS=Bos taurus GN=MYH2 PE=2 SV=1
0.0 [29..1120] [811..1931]

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Predicted Domain #1
Region A:
Residues: [1-376]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADADEYSTA PTQQEITPLQ TTATIINAIS GECITTNVDF FVSLDKFKQF IARKWKIPPD  60
   61 QLLILLPYGN KLKPSMFKEL LINRSFTLND FYVYDRRLFS LVSKPTPTNL LTSKDSNPMN 120
  121 SPNSNDLTET LEYLIKNSHI SQYQGSDTIM IKPMPSPLED ADVDLSRLNY HSVTSLLTTN 180
  181 LGWLSALEID VHYFKSLIPD IIAHIKRIFD GLTVCSQYLK LYCFDVESLY NSNVQFLNQL 240
  241 VDNGMTSKWE KCFNDTLSKL TALEGDSLQK FINIESLLEN EKSVKILNHS INGKLNKIKR 300
  301 EIDENASFRD IITVNIDRLR QMFTPNESKF ELEDQMAESF EVLVSEMRTR SRNVLDKEEE 360
  361 EFNSQEFLKS MNVMLE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.0
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [377-482]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDKKESVKTL FTISQALYSQ IGELIDLKKS LQKHAVAILG NIAFTQMEIL GIKRLLLNEC  60
   61 NKDLELYKKY EVEFAQVEDL PLIYGLYLIE KYRRLSWFQQ ILSFIS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.961 0.030 protein targeting to vacuole a.47.2 t-snare proteins

Predicted functions:

Term Confidence Notes
binding 2.24002842608348 bayes_pls_golite062009
nucleic acid binding 1.29023721388505 bayes_pls_golite062009
transcription regulator activity 1.23558162468883 bayes_pls_golite062009
DNA binding 1.22770101477594 bayes_pls_golite062009
protein binding 1.03780839342631 bayes_pls_golite062009
transcription factor activity 0.65548647141585 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.16394692014973 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [483-553]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NFNQDLELFK QNELRTRNKW VKNFGSIATV FCEDLLSSSD FKRLNEYHSH TSPPNEDEED  60
   61 ENENSIANYR Q

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.30103
Match: 2tmaA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [554-636]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLVKVSQAID NYMTQIKETD VSEPIIDLLS KTLFETKRFH IIYSNFKNNN NNSSNGNSIS  60
   61 PEGSIALKSD DVVKGYKTRI KKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.30103
Match: 2tmaA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [637-698]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESLLHEFQYS DIGHWPQGVL NTHLKPFRGS ATSINKKKFL GASVLLEPAN ISEVNIDSVS  60
   61 QA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.30103
Match: 2tmaA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [699-768]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNHQIQELES NVDDLLHQLQ LLKEENNRKS MQISEMGKKI SDLEVEKTAY RETLTNLNQE  60
   61 LARLTNEEQS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.30103
Match: 2tmaA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [769-925]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HRTEIFTLNA SFKKQLNDII SQDNEKIEKL TGDYDDVSKS RERLQMDLDE SNKKHEQEVN  60
   61 LLKADIERLG KQIVTSEKSY AETNSSSMEK GEKFETIPLA EDPGRENQIS AYTQTLQDRI 120
  121 FDIISTNIFI LENIGLLLTF DNNNNIQIRR VKGLKKG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.0
Match: 1jchA_
Description: Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
Matching Structure (courtesy of the PDB):

Predicted Domain #8
Region A:
Residues: [926-1178]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TAQSNILDES TQMLDAHDNS LIKSPVFQKL KDEYELIKSV ANGSEKDTQQ SIFLGNITQL  60
   61 YDNKLYEVAV IRRFKDIETL AKKLTKENKI KRTLLERFQR EKVTLRNFQI GDLALFLPTR 120
  121 ENVNSVGSMS SSTSSLSSSF SSVDLSTPPP LDAMSIQSSP SVIHSNVINQ ASISGRDKNK 180
  181 LMRPWAAFTA FEESTRYFLK DEKGLTKGKE WFVGRIVTLE HFVADSPSNN PFRLPKGSVW 240
  241 FQVTAVVVSY QGV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle