YRC Public Data Repository - Protein Structure Prediction

Protein:	YPR022C
Organism:	Saccharomyces cerevisiae
Length:	1133 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YPR022C.

Description	E-value	Query Range	Subject Range
YPR022C - Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to bo... YP022_YEAST - Zinc finger protein YPR022C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YPR022C PE=1...	0.0	[1..1133]	[1..1133]
ZAS1_SCHPO - Zinc finger protein zas1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=zas1 PE=2 SV=1 zas1 - zinc finger protein Zas1	0.0	[114..988]	[16..820]
gi\|6470271 - gi\|6470271\|gb\|AAF13704.1\|AF199437_1 C2H2 zinc finger protein Zas1A [Schizosaccharomyces pombe]	0.0	[186..988]	[2..768]
gi\|28922566, gi\|... - gi\|7635878\|emb\|CAB88594.1\| conserved hypothetical protein [Neurospora crassa], gi\|32412270\|ref\|XP_32... gi\|85100799 - gi\|85100799\|ref\|XP_961029.1\| hypothetical protein NCU01122 [Neurospora crassa OR74A]	0.0	[124..983]	[52..843]
ZNF300 - zinc finger protein 300 gi\|208968127 - gi\|208968127\|dbj\|BAG73902.1\| zinc finger protein 300 [synthetic construct]	0.0	[2..291]	[297..580]
gi\|254911025, gi... - gi\|33417243\|gb\|AAH55817.1\| Zfp420 protein [Mus musculus], gi\|254911025\|ref\|NP_766328.2\| zinc finger ...	0.0	[2..293]	[253..538]

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Predicted Domain #1

Region A:
Residues: [1-95]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHGKELAGRL RKRENDNDLS PNSSSSPAER FRCPHPECNK TFSRQEHLSR HKLNHWPKEI  60
   61 YVCSYVLPTT NAPCNKTFVR KDLLIRHEKR HSKVK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	68.68867
Match:	2adr__
Description:	ADR1
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [96-370]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRLSRPSKDQ ISSSNKDFSK NAPYNPSEVP LSTQSGTSTI NLIKNSVNPP PSITQESKFR  60
   61 PFLQQAQQPQ QVQQSQQPQQ IQQLQQLQFP QQLRAPLQQP MLQQQMHPQQ ASPTFPSYDP 120
  121 RIRNNGQNGN QFFNLIFDNR TGVNGFEVDA ANNNGNGNDQ NMNINPAVQQ QRYQDRNFAS 180
  181 SSYQQPLQPL TQDQQQEQYF QQQKLAQQQQ QQQQQQQQQQ QLPPQNPFGD PLTSSSSGAN 240
  241 LSVMQDLFST NFLNSDPLQS FMQELSEAPQ VSIED

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [371-471]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TFSDKNTIPP NEKPVQQDEG FQNPPVMFEL PQDNIKIPKA QPKFNDNPST SVKDNLSSQK  60
   61 LNINELKRRS SKDSGVGNNS SLNYKEQLRH SMKSVPSFFH P

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [472-995]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPLTKYKISK EKCQEMFSFV PELRYVSIES IHKSLKSFWL NFHPQYGLLH KPSFHVDKQP  60
   61 AILNLALIMT GASFLGSEYR EQISDPICGP LRWIIFSHAD FQPPSKTYII QSLLLVEGYE 120
  121 KTSTNRYLHE RSFLHHGTTI QLLRRTPSLG GHPLMVKTGK TSGENSIQDP QEVYKRWIDF 180
  181 EMLKRIAFYA FYMDTTHAVV FGYWNLFINS NQIQLTLPCP DQVWESYDLS YETLMEHGYG 240
  241 STKRDENNTF LSALMQLMKN VIQILRNNNI RRNKVNNGGI ESTPTDLEST TDWNIQSLFG 300
  301 KKILLAGIIS ILFQCQEEVN GDYFITNFRG GITDHLGLSW KDILSFAMNY WLHEVQKSCT 360
  361 DPKACRISTP SEETLTNRKI DEDNGDGLCD DDLDLLSSDN PSNCKIPVIH ISQIVLRILH 420
  421 HDYYIYAGAP WRMNVPIGRD EYDMISRRIL QFAKDPYNGG VAVVYAFQFL FEMFIIKENN 480
  481 VPTVVKSYNI NSDPVITRPY AIALTSLLIW SCNFALHGCE VSIW

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [996-1133]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DNTEASKDEC FQPDDSNGGN ILGNTDNNGS TIANNNLKEK NNYIPIESFE VYLLRMYRNL  60
   61 YVDSSLDVVS FQNDVWAKAS LLQHISNTHF LCGMMQFMRD IFNKSYWDLG REFGKLFDNC 120
  121 LERSLGKTSP TCHNMFDV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.901	0.246	cytoplasm	a.118.9	ENTH/VHS domain

Predicted Domain #6

Region A:
Residues: [630-854]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKTSGENSIQ DPQEVYKRWI DFEMLKRIAF YAFYMDTTHA VVFGYWNLFI NSNQIQLTLP  60
   61 CPDQVWESYD LSYETLMEHG YGSTKRDENN TFLSALMQLM KNVIQILRNN NIRRNKVNNG 120
  121 GIESTPTDLE STTDWNIQSL FGKKILLAGI ISILFQCQEE VNGDYFITNF RGGITDHLGL 180
  181 SWKDILSFAM NYWLHEVQKS CTDPKACRIS TPSEETLTNR KIDED

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7

Region A:
Residues: [855-997]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGDGLCDDDL DLLSSDNPSN CKIPVIHISQ IVLRILHHDY YIYAGAPWRM NVPIGRDEYD  60
   61 MISRRILQFA KDPYNGGVAV VYAFQFLFEM FIIKENNVPT VVKSYNINSD PVITRPYAIA 120
  121 LTSLLIWSCN FALHGCEVSI WDN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8

Region A:
Residues: [998-1133]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TEASKDECFQ PDDSNGGNIL GNTDNNGSTI ANNNLKEKNN YIPIESFEVY LLRMYRNLYV  60
   61 DSSLDVVSFQ NDVWAKASLL QHISNTHFLC GMMQFMRDIF NKSYWDLGRE FGKLFDNCLE 120
  121 RSLGKTSPTC HNMFDV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.901	a.118.9	ENTH/VHS domain

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits