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View Structure Prediction Details

Protein: SRP72
Organism: Saccharomyces cerevisiae
Length: 646 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SRP72.

Description E-value Query
Range
Subject
Range
gi|33640682, gi|... - gi|33862569|ref|NP_894129.1| TPR repeat-containing protein [Prochlorococcus marinus str. MIT 9313], ...
2.0E-85 [1..601] [458..1025]
gi|23125541, gi|... - gi|23125541|ref|ZP_00107470.1| COG0457: FOG: TPR repeat [Nostoc punctiforme PCC 73102], gi|186684862...
2.0E-81 [3..549] [52..591]
gi|27499606 - gi|27499606|gb|AAO17363.1| O-linked GlcNAc transferase [Mus musculus]
6.0E-80 [50..534] [24..499]
gi|31873825 - gi|31873825|emb|CAD97853.1| hypothetical protein [Homo sapiens]
8.0E-80 [50..534] [24..499]
OGT1_RAT - UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Rattus norvegicu...
2.0E-79 [50..534] [14..489]
gi|5052534 - gi|5052534|gb|AAD38597.1|AF145622_1 BcDNA.GH04245 [Drosophila melanogaster]
3.0E-76 [50..534] [53..528]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
8.0E-75 [53..534] [174..646]

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Predicted Domain #1
Region A:
Residues: [1-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKESKKMAKD NLTNLLSQLN IQLSQDEHSQ VEQTCVKLLD SGCENPADVF RRCLVAVIQQ  60
   61 DKYQKALHYL KKFKHIDDKY GRKFALEKLY IFYKLNMPDE FNTLYTAIIT DDLDTVLKKD 120
  121 IESLRGILHV RAQYCYKNG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.0
Match: 1fchA_
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [140-249]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LYQEAFKIYQ HLASHNEKDQ DSQIELSCNE RVPLSVATEL MNRSPLVTPM DESSYDLLFN  60
   61 ESFIMASVGK YDKAIELLEK ALQGATNEGY QNDINTIKLQ LSFVLQMVGK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.0
Match: 1fchA_
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [250-378]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TAQSKEILKG LLQELKADSP FSLICQNNLN AFVDFSKYNT NFNLLLRELN VEKLNTFNLQ  60
   61 TFTHEQWSNI QRNVLFLRLF NNVKIHSQES LLSRTFDKYS KLVDNVTLES YKTQAKKLYH 120
  121 HTTKTILSG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.09691
Match: 1kt1A_
Description: FKBP51, C-terminal domain; FKBP51, N-terminal domains
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [379-580]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TDGSTIGILL LTIQLLIIEK EWENAIRIGE LFLNESWKSS FEKFNDSQAI VCYILFELYK  60
   61 IKGRNNSKSV LLKKLGSVRV QLSGKIQENI PFWKHVGFEL LSMGNAKESK ALLREISNFS 120
  121 KGDADVLVDR VVSSDSLDIA QGIDLVRDID IDKLIQLGVK PLESSAKRSK NTAVSKVQKR 180
  181 KVLELKKKRK IKRLEKFLQG RD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [581-646]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSKLPDPERW LPLRDRSTYR PKKKQQGAKQ TQGGAMNKKS EQALDISKKG KPTVNKKPKN  60
   61 KKKGRK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.256 0.162 signal sequence binding a.3.1 Cytochrome c
View Download 0.230 N/A N/A a.76.1 Iron-dependent represor protein, dimerization domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle