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View Structure Prediction Details

Protein: SRP72
Organism: Saccharomyces cerevisiae
Length: 646 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SRP72.

Description E-value Query
Range
Subject
Range
gi|33640682, gi|... - gi|33862569|ref|NP_894129.1| TPR repeat-containing protein [Prochlorococcus marinus str. MIT 9313], ...
2.0E-85 [1..601] [458..1025]
gi|23125541, gi|... - gi|23125541|ref|ZP_00107470.1| COG0457: FOG: TPR repeat [Nostoc punctiforme PCC 73102], gi|186684862...
2.0E-81 [3..549] [52..591]
gi|27499606 - gi|27499606|gb|AAO17363.1| O-linked GlcNAc transferase [Mus musculus]
6.0E-80 [50..534] [24..499]
gi|31873825 - gi|31873825|emb|CAD97853.1| hypothetical protein [Homo sapiens]
8.0E-80 [50..534] [24..499]
OGT1_RAT - UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Rattus norvegicu...
2.0E-79 [50..534] [14..489]
gi|5052534 - gi|5052534|gb|AAD38597.1|AF145622_1 BcDNA.GH04245 [Drosophila melanogaster]
3.0E-76 [50..534] [53..528]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
8.0E-75 [53..534] [174..646]

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Predicted Domain #1
Region A:
Residues: [1-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKESKKMAKD NLTNLLSQLN IQLSQDEHSQ VEQTCVKLLD SGCENPADVF RRCLVAVIQQ  60
   61 DKYQKALHYL KKFKHIDDKY GRKFALEKLY IFYKLNMPDE FNTLYTAIIT DDLDTVLKKD 120
  121 IESLRGILHV RAQYCYKNG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.0
Match: 1fchA_
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [140-249]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LYQEAFKIYQ HLASHNEKDQ DSQIELSCNE RVPLSVATEL MNRSPLVTPM DESSYDLLFN  60
   61 ESFIMASVGK YDKAIELLEK ALQGATNEGY QNDINTIKLQ LSFVLQMVGK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.0
Match: 1fchA_
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [250-378]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TAQSKEILKG LLQELKADSP FSLICQNNLN AFVDFSKYNT NFNLLLRELN VEKLNTFNLQ  60
   61 TFTHEQWSNI QRNVLFLRLF NNVKIHSQES LLSRTFDKYS KLVDNVTLES YKTQAKKLYH 120
  121 HTTKTILSG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.09691
Match: 1kt1A_
Description: FKBP51, C-terminal domain; FKBP51, N-terminal domains
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [379-580]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TDGSTIGILL LTIQLLIIEK EWENAIRIGE LFLNESWKSS FEKFNDSQAI VCYILFELYK  60
   61 IKGRNNSKSV LLKKLGSVRV QLSGKIQENI PFWKHVGFEL LSMGNAKESK ALLREISNFS 120
  121 KGDADVLVDR VVSSDSLDIA QGIDLVRDID IDKLIQLGVK PLESSAKRSK NTAVSKVQKR 180
  181 KVLELKKKRK IKRLEKFLQG RD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [581-646]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSKLPDPERW LPLRDRSTYR PKKKQQGAKQ TQGGAMNKKS EQALDISKKG KPTVNKKPKN  60
   61 KKKGRK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle